Literature DB >> 28522575

Amplification of mixed lineage leukemia gene perturbs hematopoiesis and cooperates with partial tandem duplication to induce acute myeloid leukemia.

Bon Ham Yip1, Chiou Tsun Tsai1, Jayant K Rane1, Winston Vetharoy1, Eduardo Anguita2, Shuo Dong3, Michael A Caligiuri4, Chi Wai Eric So5.   

Abstract

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Year:  2017        PMID： 28522575      PMCID： PMC6643733          DOI： 10.3324/haematol.2016.161406

Source DB:  PubMed          Journal:  Haematologica        ISSN： 0390-6078            Impact factor:   9.941


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  15 in total

1.  MLL partial tandem duplication leukemia cells are sensitive to small molecule DOT1L inhibition.

Authors:  Michael W M Kühn; Michael J Hadler; Scott R Daigle; Richard P Koche; Andrei V Krivtsov; Edward J Olhava; Michael A Caligiuri; Gang Huang; James E Bradner; Roy M Pollock; Scott A Armstrong
Journal:  Haematologica       Date:  2015-01-16       Impact factor: 9.941

2.  SnapShot: Acute myeloid leukemia.

Authors:  Bernd B Zeisig; Austin G Kulasekararaj; Ghulam J Mufti; Chi Wai Eric So
Journal:  Cancer Cell       Date:  2012-11-13       Impact factor: 31.743

3.  The MLL partial tandem duplication: evidence for recessive gain-of-function in acute myeloid leukemia identifies a novel patient subgroup for molecular-targeted therapy.

Authors:  Susan P Whitman; Shujun Liu; Tamara Vukosavljevic; Laura J Rush; Li Yu; Chunhui Liu; Marko I Klisovic; Kati Maharry; Martin Guimond; Matthew P Strout; Brian Becknell; Adrienne Dorrance; Rebecca B Klisovic; Christoph Plass; Clara D Bloomfield; Guido Marcucci; Michael A Caligiuri
Journal:  Blood       Date:  2005-03-17       Impact factor: 22.113

4.  MLL amplification in acute myeloid leukemia.

Authors:  Juan C Pajuelo-Gámez; José Cervera; Zaida García-Casado; Armando V Mena-Durán; Ana Valencia; Eva Barragán; Esperanza Such; Pascual Bolufer; Miguel A Sanz
Journal:  Cancer Genet Cytogenet       Date:  2007-04-15

5.  Expression analyses identify MLL as a prominent target of 11q23 amplification and support an etiologic role for MLL gain of function in myeloid malignancies.

Authors:  Bruce Poppe; Jo Vandesompele; Claudia Schoch; Charlotta Lindvall; Krzysztof Mrozek; Clara D Bloomfield; H Berna Beverloo; Lucienne Michaux; Nicole Dastugue; Christian Herens; Nurten Yigit; Anne De Paepe; Anne Hagemeijer; Frank Speleman
Journal:  Blood       Date:  2003-08-28       Impact factor: 22.113

6.  Eradicating acute myeloid leukemia in a Mll(PTD/wt):Flt3(ITD/wt) murine model: a path to novel therapeutic approaches for human disease.

Authors:  Kelsie M Bernot; John S Nemer; Ramasamy Santhanam; Shujun Liu; Nicholas A Zorko; Susan P Whitman; Kathryn E Dickerson; Mengzi Zhang; Xiaojuan Yang; Kathleen K McConnell; Elshafa H Ahmed; Maura R Muñoz; Ronald F Siebenaler; Gabriel G Marcucci; Bethany L Mundy-Bosse; Daniel L Brook; Sabrina Garman; Adrienne M Dorrance; Xiaoli Zhang; Jianying Zhang; Robert J Lee; William Blum; Michael A Caligiuri; Guido Marcucci
Journal:  Blood       Date:  2013-10-01       Impact factor: 22.113

7.  Functional crosstalk between Bmi1 and MLL/Hoxa9 axis in establishment of normal hematopoietic and leukemic stem cells.

Authors:  Lan-Lan Smith; Jenny Yeung; Bernd B Zeisig; Nikolay Popov; Ivo Huijbers; Josephine Barnes; Amanda J Wilson; Erdogan Taskesen; Ruud Delwel; Jesús Gil; Maarten Van Lohuizen; Chi Wai Eric So
Journal:  Cell Stem Cell       Date:  2011-06-03       Impact factor: 24.633

8.  Synthetic lethal targeting of oncogenic transcription factors in acute leukemia by PARP inhibitors.

Authors:  Maria Teresa Esposito; Lu Zhao; Tsz Kan Fung; Jayant K Rane; Amanda Wilson; Nadine Martin; Jesus Gil; Anskar Y Leung; Alan Ashworth; Chi Wai Eric So
Journal:  Nat Med       Date:  2015-11-23       Impact factor: 53.440

Review 9.  Mixed lineage leukemia protein in normal and leukemic stem cells.

Authors:  Bon Ham Yip; Chi Wai Eric So
Journal:  Exp Biol Med (Maywood)       Date:  2013-03

10.  Small-molecule inhibition of MLL activity by disruption of its interaction with WDR5.

Authors:  Guillermo Senisterra; Hong Wu; Abdellah Allali-Hassani; Gregory A Wasney; Dalia Barsyte-Lovejoy; Ludmila Dombrovski; Aiping Dong; Kong T Nguyen; David Smil; Yuri Bolshan; Taraneh Hajian; Hao He; Alma Seitova; Irene Chau; Fengling Li; Gennadiy Poda; Jean-François Couture; Peter J Brown; Rima Al-Awar; Matthieu Schapira; Cheryl H Arrowsmith; Masoud Vedadi
Journal:  Biochem J       Date:  2013-01-01       Impact factor: 3.857
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  1 in total

1.  Breakage-Fusion-Bridge Events Trigger Complex Genome Rearrangements and Amplifications in Developmentally Arrested T Cell Lymphomas.

Authors:  Joy J Bianchi; Valentine Murigneux; Marie Bedora-Faure; Chloé Lescale; Ludovic Deriano
Journal:  Cell Rep       Date:  2019-06-04       Impact factor: 9.423
  1 in total

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