Alen Zabotti1, Francesca Bandinelli2, Alberto Batticciotto3, Carlo Alberto Scirè4,5, Annamaria Iagnocco6, Garifallia Sakellariou7. 1. Rheumatology Clinic, Department of Medical and Biological Sciences, University Hospital Santa Maria della Misericordia, Udine. 2. Rheumatology Unit, Azienda Sanitaria di Firenze, S. Giovanni di Dio Hospital, Florence. 3. Rheumatology Unit, L. Sacco University Hospital. 4. Epidemiology Unit of the Italian Society for Rheumatology (SIR), Milan. 5. Department of Medical Sciences, Section of Rheumatology, University of Ferrara, Ferrara. 6. Dipartimento di Scienze Cliniche e Biologiche, Università degli Studi di Torino, Turin. 7. Division of Rheumatology, IRCCS Policlinico San Matteo Foundation, University of Pavia, Pavia, Italy.
Abstract
Objective: To systematically review the role of musculoskeletal US in patients suffering from PsA or psoriasis (Pso) in terms of prevalence, diagnosis, prognosis, monitoring and treatment. Methods: A systematic literature review was conducted through medical databases (MEDLINE via PubMed, Embase) and the grey literature up to September 2015 to inform a new study of the Musculoskeletal Ultrasound Study Group of the Italian Society for Rheumatology. All articles reporting data on musculoskeletal US in PsA or Pso were included and extracted according to the underlying clinical question. Results: A total of 86 publications were included. The prevalence of US abnormalities showed a wide range for each examined feature (e.g. 37-95% for entheses thickness of the lower limbs). The performance of US for diagnosis of disease or elementary lesions was variable across studies, but no study evaluated the overall performance of US in addition to clinical findings for diagnosing PsA. Considering US in defining PsA and Pso prognosis, several works focused on US of entheses of lower limbs in Pso, while for the monitoring of PsA activity five different scoring systems were identified. Last, the results of the role of US in guiding intra-articular interventions were controversial for the clinical outcomes, but in favour of US for accuracy. Conclusion: despite the recognized importance of US in the management of PsA and Pso, this review clearly demonstrated the need of pivotal research in order to optimize the use of US in the diagnosis and monitoring of psoriatic disease.
Objective: To systematically review the role of musculoskeletal US in patients suffering from PsA or psoriasis (Pso) in terms of prevalence, diagnosis, prognosis, monitoring and treatment. Methods: A systematic literature review was conducted through medical databases (MEDLINE via PubMed, Embase) and the grey literature up to September 2015 to inform a new study of the Musculoskeletal Ultrasound Study Group of the Italian Society for Rheumatology. All articles reporting data on musculoskeletal US in PsA or Pso were included and extracted according to the underlying clinical question. Results: A total of 86 publications were included. The prevalence of US abnormalities showed a wide range for each examined feature (e.g. 37-95% for entheses thickness of the lower limbs). The performance of US for diagnosis of disease or elementary lesions was variable across studies, but no study evaluated the overall performance of US in addition to clinical findings for diagnosing PsA. Considering US in defining PsA and Pso prognosis, several works focused on US of entheses of lower limbs in Pso, while for the monitoring of PsA activity five different scoring systems were identified. Last, the results of the role of US in guiding intra-articular interventions were controversial for the clinical outcomes, but in favour of US for accuracy. Conclusion: despite the recognized importance of US in the management of PsA and Pso, this review clearly demonstrated the need of pivotal research in order to optimize the use of US in the diagnosis and monitoring of psoriatic disease.
Authors: Garifallia Sakellariou; Carlo Alberto Scirè; Antonella Adinolfi; Alberto Batticciotto; Alessandra Bortoluzzi; Andrea Delle Sedie; Orazio De Lucia; Christian Dejaco; Oscar Massimiliano Epis; Emilio Filippucci; Luca Idolazzi; Andrea Picchianti Diamanti; Alen Zabotti; Annamaria Iagnocco; Georgios Filippou Journal: Front Med (Lausanne) Date: 2020-05-07
Authors: Alen Zabotti; Georgios Filippou; Marco Canzoni; Antonella Adinolfi; Valentina Picerno; Greta Carrara; Peter Balint; George A Bruyn; Maria Antonietta D'Agostino; Nemanja Damjanov; Andrea Delle Sedie; Emilio Filippucci; Maria Luz Gonzalez Fernandez; Hilde Berner Hammer; Zunaid Karim; Peter Mandl; Ingrid Moller; Maria Rosario Morales Lozano; Esperanza Naredo; Francesco Porta; Garifallia Sakellariou; Lene Terslev; Carlo Alberto Scirè; Annamaria Iagnocco Journal: RMD Open Date: 2019-03-08
Authors: Alen Zabotti; Dennis G McGonagle; Ivan Giovannini; Enzo Errichetti; Francesca Zuliani; Anna Zanetti; Ilaria Tinazzi; Orazio De Lucia; Alberto Batticciotto; Luca Idolazzi; Garifallia Sakellariou; Sara Zandonella Callegher; Stefania Sacco; Luca Quartuccio; Annamaria Iagnocco; Salvatore De Vita Journal: RMD Open Date: 2019-10-23
Authors: Marco Canzoni; Matteo Piga; Alen Zabotti; Carlo Alberto Scirè; Greta Carrara; Ignazio Olivieri; Annamaria Iagnocco Journal: BMJ Open Date: 2018-07-10 Impact factor: 2.692