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Literature DB >> 2851881

Effect of nedocromil sodium on the airway response to inhaled capsaicin in normal subjects.

L Hansson¹, N B Choudry, R W Fuller, N B Pride.

Abstract

In six normal subjects treatment with 4 mg nedocromil sodium failed to alter the cough and bronchoconstriction induced by inhaled capsaicin. Because nedocromil has previously been shown to inhibit reflex bronchoconstriction provoked by inhaled sulphur dioxide and inhaled bradykinin, the results suggest that inhaled capsaicin acts on different nerve fibres.

Entities: Chemical Disease Gene

Mesh：

Substances：

Year: 1988 PMID： 2851881 PMCID： PMC461571 DOI： 10.1136/thx.43.11.935

Source DB: PubMed Journal: Thorax ISSN： 0040-6376 Impact factor: 9.139

6 in total

1. Effect of nedocromil sodium on sulphur dioxide induced bronchoconstriction.

Authors: C M Dixon; R W Fuller; P J Barnes
Journal: Thorax Date: 1987-06 Impact factor: 9.139

2. A new method to determine frequency characteristics of the respiratory system.

Authors: F J Lándsér; J Nagles; M Demedts; L Billiet; K P van de Woestijne
Journal: J Appl Physiol Date: 1976-07 Impact factor: 3.531

3. The clinical development of a new agent for the treatment of airway inflammation, nedocromil sodium (Tilade).

Authors: R M Auty
Journal: Eur J Respir Dis Suppl Date: 1986

4. Bradykinin-induced bronchoconstriction in humans. Mode of action.

Authors: R W Fuller; C M Dixon; F M Cuss; P J Barnes
Journal: Am Rev Respir Dis Date: 1987-01

5. Bronchoconstrictor response to inhaled capsaicin in humans.

Authors: R W Fuller; C M Dixon; P J Barnes
Journal: J Appl Physiol (1985) Date: 1985-04

6. The effect of intravenous sodium cromoglycate on the bronchoconstriction induced by sulphur dioxide inhalation in man.

Authors: A Allistone; J G Collier; R N Davidson; R W Fuller; P S Richardson
Journal: Clin Sci (Lond) Date: 1985-02 Impact factor: 6.124

6 in total

10 in total

Review 1. Cough challenge in the assessment of cough reflex.

Authors: A H Morice; J A Kastelik; R Thompson
Journal: Br J Clin Pharmacol Date: 2001-10 Impact factor: 4.335

Review 2. Physiology and treatment of cough.

Authors: R W Fuller; D M Jackson
Journal: Thorax Date: 1990-06 Impact factor: 9.139

3. The effect of 443C81, a mu opioid receptor agonist, on the response to inhaled capsaicin in healthy volunteers.

Authors: N B Choudry; S J Gray; J Posner; R W Fuller
Journal: Br J Clin Pharmacol Date: 1991-11 Impact factor: 4.335

4. Effect of nedocromil sodium on allergen-, PAF-, histamine- and bradykinin-induced airways vasodilatation and pulmonary obstruction in the pig.

Authors: K Alving; R Matran; J M Lundberg
Journal: Br J Pharmacol Date: 1991-10 Impact factor: 8.739

Effect of nedocromil sodium on the airway response to inhaled capsaicin in normal subjects.

1. Effect of nedocromil sodium on sulphur dioxide induced bronchoconstriction.

2. A new method to determine frequency characteristics of the respiratory system.

3. The clinical development of a new agent for the treatment of airway inflammation, nedocromil sodium (Tilade).

4. Bradykinin-induced bronchoconstriction in humans. Mode of action.

5. Bronchoconstrictor response to inhaled capsaicin in humans.

6. The effect of intravenous sodium cromoglycate on the bronchoconstriction induced by sulphur dioxide inhalation in man.

Review 1. Cough challenge in the assessment of cough reflex.

Review 2. Physiology and treatment of cough.

3. The effect of 443C81, a mu opioid receptor agonist, on the response to inhaled capsaicin in healthy volunteers.

4. Effect of nedocromil sodium on allergen-, PAF-, histamine- and bradykinin-induced airways vasodilatation and pulmonary obstruction in the pig.

5. The effects of nedocromil sodium on the response to grain dust in West Australian grain workers.

Review 6. Nedocromil sodium. An updated review of its pharmacological properties and therapeutic efficacy in asthma.

7. A randomised, placebo controlled trial of inhaled salbutamol and beclomethasone for recurrent cough.

Review 8. Inhaled beta2-agonists for treating non-specific chronic cough in children.

9. Review: Effect of drugs on human cough reflex sensitivity to inhaled capsaicin.

Review 10. Inhaled corticosteroids for non-specific chronic cough in children.