Literature DB >> 2851810

Role of the Na+K+-ATPase in the cardiotonic action of cardiac glycosides.

A Schwartz1, G Grupp, E Wallick, I L Grupp, W J Ball.   

Abstract

In terms of evolution, the Na+,K+-ATPase is one of the oldest proteins. It is intriguing that this membrane-based enzyme has become biologically consistent with a multifunctional protein. One of the most interesting aspects of the Na+,K+-ATPase is that it contains a specific receptor domain for the oldest plant origin cardiotonic drug and that it is involved in the regulation of myocardial contractility.

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Year:  1988        PMID： 2851810

Source DB:  PubMed          Journal:  Prog Clin Biol Res        ISSN： 0361-7742


  7 in total

1.  Regulation of Na/K-ATPase beta1-subunit gene expression by ouabain and other hypertrophic stimuli in neonatal rat cardiac myocytes.

Authors:  P Kometiani; J Tian; J Li; Z Nabih; G Gick; Z Xie
Journal:  Mol Cell Biochem       Date:  2000-12       Impact factor: 3.396

2.  Ouabain facilitates cardiac differentiation of mouse embryonic stem cells through ERK1/2 pathway.

Authors:  Yee-ki Lee; Kwong-man Ng; Wing-hon Lai; Cornelia Man; Deborah K Lieu; Chu-pak Lau; Hung-fat Tse; Chung-wah Siu
Journal:  Acta Pharmacol Sin       Date:  2010-12-13       Impact factor: 6.150

3.  Involvement of mitogen-activated protein kinases and reactive oxygen species in the inotropic action of ouabain on cardiac myocytes. A potential role for mitochondrial K(ATP) channels.

Authors:  Jiang Tian; Jiang Liu; Keith D Garlid; Joseph I Shapiro; Zijian Xie
Journal:  Mol Cell Biochem       Date:  2003-01       Impact factor: 3.396

4.  Different roles of the cardiac Na+/Ca2+-exchanger in ouabain-induced inotropy, cell signaling, and hypertrophy.

Authors:  Yan Bai; Eric E Morgan; David R Giovannucci; Sandrine V Pierre; Kenneth D Philipson; Amir Askari; Lijun Liu
Journal:  Am J Physiol Heart Circ Physiol       Date:  2012-11-30       Impact factor: 4.733

5.  Functional expression of the alpha 2 and alpha 3 isoforms of the Na,K-ATPase in baculovirus-infected insect cells.

Authors:  G Blanco; Z J Xie; R W Mercer
Journal:  Proc Natl Acad Sci U S A       Date:  1993-03-01       Impact factor: 11.205

6.  Ischemia/reperfusion-induced alterations of enzymatic and signaling functions of the rat cardiac Na+/K+-ATPase: protection by ouabain preconditioning.

Authors:  Aude Belliard; Gaurav K Gulati; Qiming Duan; Rosana Alves; Shannon Brewer; Namrata Madan; Yoann Sottejeau; Xiaoliang Wang; Jennifer Kalisz; Sandrine V Pierre
Journal:  Physiol Rep       Date:  2016-10

7.  Ouabain prevents pathological cardiac hypertrophy and heart failure through activation of phosphoinositide 3-kinase α in mouse.

Authors:  Jian Wu; Daxiang Li; Lingling Du; Mustafa Baldawi; Marjorie E Gable; Amir Askari; Lijun Liu
Journal:  Cell Biosci       Date:  2015-11-18       Impact factor: 7.133
  7 in total

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