Literature DB >> 28517989

Economics of Cancer Medicines: For Whose Benefit?

Bishal Gyawali1, Richard Sullivan1,2.   

Abstract

Although new cancer drugs are continually getting approved and used, the value that these drugs add is very debatable. Because of the skyrocketing cost of the new drugs, each new approval represents a multibillion market. However, unlike other branches of economics, cancer drugs are intricately associated with socio-political issues, emotional overlay, public pressure, industry manipulation and propaganda. In this article, we review the value added by new cancer drugs and examine the socio-political agenda around them with highlights on the increasing gulf between high-income and low-middle income countries regarding the affordability to these drugs. Finally, we also suggest a way forward to address this highly complex issue.

Entities:  

Keywords:  WHO essential medicine list; cancer drugs; financial toxicity; low-middle income countries; pharmacoeconomics; value

Mesh:

Substances:

Year:  2017        PMID: 28517989     DOI: 10.1080/20502877.2017.1314885

Source DB:  PubMed          Journal:  New Bioeth        ISSN: 2050-2877


  15 in total

Review 1.  Checkpoint Inhibitors, Palliative Care, or Hospice.

Authors:  Mellar P Davis; Rajiv Panikkar
Journal:  Curr Oncol Rep       Date:  2018-01-19       Impact factor: 5.075

2.  The OlympiAD trial: who won the gold?

Authors:  Bishal Gyawali
Journal:  Ecancermedicalscience       Date:  2017-12-06

3.  Reverse swing-M, phase 1 study of repurposing mebendazole in recurrent high-grade glioma.

Authors:  Vijay M Patil; Arti Bhelekar; Nandini Menon; Atanu Bhattacharjee; Vijai Simha; Ram Abhinav; Anuja Abhyankar; Epari Sridhar; Abhishek Mahajan; Ameya D Puranik; Nilendu Purandare; Amit Janu; Ankita Ahuja; Rahul Krishnatry; Tejpal Gupta; Rakesh Jalali
Journal:  Cancer Med       Date:  2020-05-13       Impact factor: 4.452

4.  Phase III Non-inferiority Study Evaluating Efficacy and Safety of Low Dose Gemcitabine Compared to Standard Dose Gemcitabine With Platinum in Advanced Squamous Lung Cancer.

Authors:  Vijay Patil; Vanita Noronha; Amit Joshi; Anuradha Chougule; Sadhana Kannan; Atanu Bhattacharjee; Supriya Goud; Sucheta More; Arun Chandrasekharan; Nandini Menon; Sujay Srinivas; Dilip Harindran Vallathol; Hollis Dsouza; Swaratika Majumdar; Sudeep Das; Abhinav Zawar; Satvik Khaddar; Amit Kumar; Gunjesh Singh; Kanteti Aditya Pavan Kumar; Rahul Ravind; Vaishakhi Trivedi; Vichitra Behel; Abhishek Mahajan; Amit Janu; Nilendu Purandare; Kumar Prabhash
Journal:  EClinicalMedicine       Date:  2019-04-09

5.  The 'molecularly unstratified' patient: a focus for moral, psycho-social and societal research.

Authors:  J Hordern; T Maughan; T Feiler; L Morrell; R Horne; R Sullivan
Journal:  Biomed Hub       Date:  2017-11-21

6.  Prospective Survey of Financial Toxicity Measured by the Comprehensive Score for Financial Toxicity in Japanese Patients With Cancer.

Authors:  Kazunori Honda; Bishal Gyawali; Masashi Ando; Ryosuke Kumanishi; Kyoko Kato; Keiji Sugiyama; Seiichiro Mitani; Toshiki Masuishi; Yukiya Narita; Hideaki Bando; Hiroya Taniguchi; Shigenori Kadowaki; Takashi Ura; Kei Muro
Journal:  J Glob Oncol       Date:  2019-05

7.  Design characteristics, risk of bias, and reporting of randomised controlled trials supporting approvals of cancer drugs by European Medicines Agency, 2014-16: cross sectional analysis.

Authors:  Huseyin Naci; Courtney Davis; Jelena Savović; Julian P T Higgins; Jonathan A C Sterne; Bishal Gyawali; Xochitl Romo-Sandoval; Nicola Handley; Christopher M Booth
Journal:  BMJ       Date:  2019-09-18

Review 8.  A Comprehensive Review of Calcium Electroporation -A Novel Cancer Treatment Modality.

Authors:  Stine K Frandsen; Mille Vissing; Julie Gehl
Journal:  Cancers (Basel)       Date:  2020-01-25       Impact factor: 6.639

9.  Cancer treatment in the last 6 months of life: when inaction can outperform action.

Authors:  Bishal Gyawali; Saroj Niraula
Journal:  Ecancermedicalscience       Date:  2018-04-18

10.  A prospective survey of comprehensive score for financial toxicity in Japanese cancer patients: report on a pilot study.

Authors:  Kazunori Honda; Bishal Gyawali; Masashi Ando; Keiji Sugiyama; Seiichiro Mitani; Toshiki Masuishi; Yukiya Narita; Hiroya Taniguchi; Shigenori Kadowaki; Takashi Ura; Kei Muro
Journal:  Ecancermedicalscience       Date:  2018-07-05
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