F Pak1,2, A Farajollahi1,2, Z Miabi1,2. 1. Faculty of medicine, Tabriz University of medical sciences, tabriz. 2. Faculty of medicine, Tabriz University of medical sciences.
Abstract
PURPOSE: To asses a series of basic dosimetric properties such as reproducibility, linearity, tissue equivalency, dose rate and energy independency for NIPAM polymer gel dosimeter. METHODS: The NIPAM gel was manufactured according to the method, described by senden et al (2006). The gels were irradiated approximately 2 h after manufacturing and MR images of the gel were made 24 h after irradiation. Transverse relaxation rates (R2=T2?1 ) were obtained from the signal decay data using the proper data analyzer. In order to investigate the absorbed dose response reproducibility, the experiment was repeated three times using the same batch of monomer, irradiation method, scanning parameters and conditions, also with analyzing two set of the gel with different batches of chemical the effect of different batches were investigated . For assessing if the NIPAM gel dosimeter response is dependent on different photon energies, two sets of NIPAM gel were irradiated using a 9 MV linear accelerator and a 60co. The effect of different dose rate on gel response was studied in SSD of 80, 90, 100, 110 and 120 and radiation beam were calibrated to give 5Gy in each SSD. To investigate the linearity of the gel, the vials were irradiated from 1 to 35 Gy. In order to verify tissue equivalency, effective atomic number and relative electron density of NIPAM dosimeter were calculated using CT number, and compared with tissue. RESULTS: This polymer gel found to be tissue equivalent. The results showed that the dose response of NIPAM polymer gel is highly reproducible in same and different batches of chemical and its response was linear up to 26 Gy. Energy and dose rate had no effect on NIPAM gel response. CONCLUSIONS: NIPAM gel dosimeter appears to be a promising dosimeter in all aspects of dosimetric properties which were assessed in this study.
PURPOSE: To asses a series of basic dosimetric properties such as reproducibility, linearity, tissue equivalency, dose rate and energy independency for NIPAMpolymer gel dosimeter. METHODS: The NIPAM gel was manufactured according to the method, described by senden et al (2006). The gels were irradiated approximately 2 h after manufacturing and MR images of the gel were made 24 h after irradiation. Transverse relaxation rates (R2=T2?1 ) were obtained from the signal decay data using the proper data analyzer. In order to investigate the absorbed dose response reproducibility, the experiment was repeated three times using the same batch of monomer, irradiation method, scanning parameters and conditions, also with analyzing two set of the gel with different batches of chemical the effect of different batches were investigated . For assessing if the NIPAM gel dosimeter response is dependent on different photon energies, two sets of NIPAM gel were irradiated using a 9 MV linear accelerator and a 60co. The effect of different dose rate on gel response was studied in SSD of 80, 90, 100, 110 and 120 and radiation beam were calibrated to give 5Gy in each SSD. To investigate the linearity of the gel, the vials were irradiated from 1 to 35 Gy. In order to verify tissue equivalency, effective atomic number and relative electron density of NIPAM dosimeter were calculated using CT number, and compared with tissue. RESULTS: This polymer gel found to be tissue equivalent. The results showed that the dose response of NIPAMpolymer gel is highly reproducible in same and different batches of chemical and its response was linear up to 26 Gy. Energy and dose rate had no effect on NIPAM gel response. CONCLUSIONS:NIPAM gel dosimeter appears to be a promising dosimeter in all aspects of dosimetric properties which were assessed in this study.
Keywords:
Atom irradiation effects; Chemical analysis; Data analysis; Gels; Linear accelerators; Manufacturing; Medical imaging; Medical magnetic resonance imaging; Photons; Polymers