Literature DB >> 28516426

Characterization of Medication Use in a Multicenter Sample of Pediatric Inpatients with Autism Spectrum Disorder.

Logan K Wink1, Ernest V Pedapati2, Ryan Adams3, Craig A Erickson2, Kahsi A Pedersen4, Eric M Morrow5, Desmond Kaplan6, Matthew Siegel7.   

Abstract

Nearly 11% of youth with Autism Spectrum Disorder (ASD) undergo psychiatric hospitalization, and 65% are treated with psychotropic medication. Here we characterize psychotropic medication usage in subjects enrolled in the Autism Inpatient Collection. Participant psychotropic medication usage rates topped 90% at admission and discharge, though there was a decline at 2-month follow-up. Antipsychotics, ADHD medications, and sleep aids were the most commonly reported classes of medications. The impact of age, gender, and non-verbal IQ on medication usage rates was minimal, though age and IQ may play a role in prescribing practices. Future work is indicated to explore medication usage trends, the impact of clinical factors on medication use rates, and the safety of psychotropic medications in youth with ASD.

Entities:  

Keywords:  Antipsychotics; Autism; Autism Spectrum Disorder; Medication; Psychiatric hospitalization

Mesh：

Substances：

Year:  2018        PMID： 28516426     DOI： 10.1007/s10803-017-3153-x

Source DB:  PubMed          Journal:  J Autism Dev Disord        ISSN： 0162-3257


  22 in total

1.  Randomized, controlled, crossover trial of methylphenidate in pervasive developmental disorders with hyperactivity.

Authors: 
Journal:  Arch Gen Psychiatry       Date:  2005-11

Review 2.  Antipsychotic Use Trends in Youth With Autism Spectrum Disorder and/or Intellectual Disability: A Meta-Analysis.

Authors:  Su Young Park; Chiara Cervesi; Britta Galling; Silvia Molteni; Frozan Walyzada; Stephanie H Ameis; Tobias Gerhard; Mark Olfson; Christoph U Correll
Journal:  J Am Acad Child Adolesc Psychiatry       Date:  2016-04-07       Impact factor: 8.829

3.  Prevalence of chronic gastrointestinal symptoms in children with autism and autistic spectrum disorders.

Authors:  Cynthia A Molloy; Patricia Manning-Courtney
Journal:  Autism       Date:  2003-06

4.  Aripiprazole in the treatment of irritability in children and adolescents with autistic disorder.

Authors:  Randall Owen; Linmarie Sikich; Ronald N Marcus; Patricia Corey-Lisle; George Manos; Robert D McQuade; William H Carson; Robert L Findling
Journal:  Pediatrics       Date:  2009-12       Impact factor: 7.124

5.  Psychiatric Hospitalization of Children With Autism or Intellectual Disability: Consensus Statements on Best Practices.

Authors:  Kelly McGuire; Craig Erickson; Robin L Gabriels; Desmond Kaplan; Carla Mazefsky; John McGonigle; Jarle Meservy; Ernest Pedapati; Joseph Pierri; Logan Wink; Matthew Siegel
Journal:  J Am Acad Child Adolesc Psychiatry       Date:  2015-12       Impact factor: 8.829

6.  Lack of efficacy of citalopram in children with autism spectrum disorders and high levels of repetitive behavior: citalopram ineffective in children with autism.

Authors:  Bryan H King; Eric Hollander; Linmarie Sikich; James T McCracken; Lawrence Scahill; Joel D Bregman; Craig L Donnelly; Evdokia Anagnostou; Kimberly Dukes; Lisa Sullivan; Deborah Hirtz; Ann Wagner; Louise Ritz
Journal:  Arch Gen Psychiatry       Date:  2009-06

7.  Psychiatric hospitalization among children with autism spectrum disorders.

Authors:  David S Mandell
Journal:  J Autism Dev Disord       Date:  2007-11-02

8.  The aberrant behavior checklist: a behavior rating scale for the assessment of treatment effects.

Authors:  M G Aman; N N Singh; A W Stewart; C J Field
Journal:  Am J Ment Defic       Date:  1985-03

9.  Risperidone in children with autism and serious behavioral problems.

Authors:  James T McCracken; James McGough; Bhavik Shah; Pegeen Cronin; Daniel Hong; Michael G Aman; L Eugene Arnold; Ronald Lindsay; Patricia Nash; Jill Hollway; Christopher J McDougle; David Posey; Naomi Swiezy; Arlene Kohn; Lawrence Scahill; Andres Martin; Kathleen Koenig; Fred Volkmar; Deirdre Carroll; Allison Lancor; Elaine Tierney; Jaswinder Ghuman; Nilda M Gonzalez; Marco Grados; Benedetto Vitiello; Louise Ritz; Mark Davies; James Robinson; Don McMahon
Journal:  N Engl J Med       Date:  2002-08-01       Impact factor: 91.245

10.  The autism inpatient collection: methods and preliminary sample description.

Authors:  Matthew Siegel; Kahsi A Smith; Carla Mazefsky; Robin L Gabriels; Craig Erickson; Desmond Kaplan; Eric M Morrow; Logan Wink; Susan L Santangelo
Journal:  Mol Autism       Date:  2015-11-10       Impact factor: 7.509
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  5 in total

1.  Behavioral Outcomes of Specialized Psychiatric Hospitalization in the Autism Inpatient Collection (AIC): A Multisite Comparison.

Authors:  Kahsi A Pedersen; Susan L Santangelo; Robin L Gabriels; Giulia Righi; Michael Erard; Matthew Siegel
Journal:  J Autism Dev Disord       Date:  2018-11

2.  The Severe End of the Spectrum: Insights and Opportunities from the Autism Inpatient Collection (AIC).

Authors:  Matthew Siegel
Journal:  J Autism Dev Disord       Date:  2018-11

3.  A Randomized Placebo-Controlled Cross-Over Pilot Study of Riluzole for Drug-Refractory Irritability in Autism Spectrum Disorder.

Authors:  Logan K Wink; Ryan Adams; Paul S Horn; Charles R Tessier; Andrew P Bantel; Michael Hong; Rebecca C Shaffer; Ernest V Pedapati; Craig A Erickson
Journal:  J Autism Dev Disord       Date:  2018-09

4.  Emotion Dysregulation is Substantially Elevated in Autism Compared to the General Population: Impact on Psychiatric Services.

Authors:  Caitlin M Conner; Josh Golt; Rebecca Shaffer; Giulia Righi; Matthew Siegel; Carla A Mazefsky
Journal:  Autism Res       Date:  2020-12-08       Impact factor: 5.216

Review 5.  Gender Trends in Psychotropic Medication Use in Autism.

Authors:  Christopher R Huber; Zachary Fanaro; Varun Soti
Journal:  Cureus       Date:  2022-06-30
  5 in total

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