| Literature DB >> 28516249 |
A Hiseni-Kamberi1, W-D Maier1, K Junker2, M Argirov3.
Abstract
A 67-year-old man presented with fever, night sweat and abdominal complaints for about 4 weeks. Ultrasound and a computed tomography scan showed distinct ascites as the main finding, presenting as exsudate with predominating lymphoid cells. Because of long-term immunosuppressive therapy with the tumor necrosis factor (TNF)-α inhibitor golimumab for psoriasis, the suspicion for a possible tuberculous peritonitis arose. This was confirmed with an enzyme-linked immunospot assay, a high level of adenosine deaminase in the ascites and a peritoneum which was studded with multiple whitish nodules, corresponding to granulomas with giant cells. With a standard antituberculous regimen the symptoms were quickly relieved and finally complete restitution was achieved.Entities:
Keywords: Adenosine deaminase; Ascites; Golimumab; Tuberculous peritonitis; Tumor necrosis factor-α inhibitors
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Year: 2017 PMID: 28516249 DOI: 10.1007/s00108-017-0254-8
Source DB: PubMed Journal: Internist (Berl) ISSN: 0020-9554 Impact factor: 0.743