Literature DB >> 28515434

Cerebral blood flow regulation and neurovascular dysfunction in Alzheimer disease.

Kassandra Kisler1, Amy R Nelson1, Axel Montagne1, Berislav V Zlokovic1.   

Abstract

Cerebral blood flow (CBF) regulation is essential for normal brain function. The mammalian brain has evolved a unique mechanism for CBF control known as neurovascular coupling. This mechanism ensures a rapid increase in the rate of CBF and oxygen delivery to activated brain structures. The neurovascular unit is composed of astrocytes, mural vascular smooth muscle cells and pericytes, and endothelia, and regulates neurovascular coupling. This Review article examines the cellular and molecular mechanisms within the neurovascular unit that contribute to CBF control, and neurovascular dysfunction in neurodegenerative disorders such as Alzheimer disease.

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Mesh：

Year:  2017        PMID： 28515434      PMCID： PMC5759779          DOI： 10.1038/nrn.2017.48

Source DB:  PubMed          Journal:  Nat Rev Neurosci        ISSN： 1471-003X            Impact factor:   34.870


  182 in total

Review 1.  Vascular inward rectifier K+ channels as external K+ sensors in the control of cerebral blood flow.

Authors:  Thomas A Longden; Mark T Nelson
Journal:  Microcirculation       Date:  2015-04       Impact factor: 2.628

2.  Pericyte contraction induced by oxidative-nitrative stress impairs capillary reflow despite successful opening of an occluded cerebral artery.

Authors:  Muge Yemisci; Yasemin Gursoy-Ozdemir; Atay Vural; Alp Can; Kamil Topalkara; Turgay Dalkara
Journal:  Nat Med       Date:  2009-08-30       Impact factor: 53.440

3.  Differential regional dysfunction of the hippocampal formation among elderly with memory decline and Alzheimer's disease.

Authors:  S A Small; G M Perera; R DeLaPaz; R Mayeux; Y Stern
Journal:  Ann Neurol       Date:  1999-04       Impact factor: 10.422

4.  SOD1 rescues cerebral endothelial dysfunction in mice overexpressing amyloid precursor protein.

Authors:  C Iadecola; F Zhang; K Niwa; C Eckman; S K Turner; E Fischer; S Younkin; D R Borchelt; K K Hsiao; G A Carlson
Journal:  Nat Neurosci       Date:  1999-02       Impact factor: 24.884

5.  P-450 epoxygenase and NO synthase inhibitors reduce cerebral blood flow response to N-methyl-D-aspartate.

Authors:  A Bhardwaj; F J Northington; J R Carhuapoma; J R Falck; D R Harder; R J Traystman; R C Koehler
Journal:  Am J Physiol Heart Circ Physiol       Date:  2000-10       Impact factor: 4.733

6.  Early loss of pericytes and perivascular stromal cell-induced scar formation after stroke.

Authors:  Francisco Fernández-Klett; Jason R Potas; Diana Hilpert; Katja Blazej; Josefine Radke; Jojanneke Huck; Odilo Engel; Werner Stenzel; Guillem Genové; Josef Priller
Journal:  J Cereb Blood Flow Metab       Date:  2012-12-19       Impact factor: 6.200

7.  Accelerated pericyte degeneration and blood-brain barrier breakdown in apolipoprotein E4 carriers with Alzheimer's disease.

Authors:  Matthew R Halliday; Sanket V Rege; Qingyi Ma; Zhen Zhao; Carol A Miller; Ethan A Winkler; Berislav V Zlokovic
Journal:  J Cereb Blood Flow Metab       Date:  2016-01       Impact factor: 6.200

Review 8.  The pericyte: a forgotten cell type with important implications for Alzheimer's disease?

Authors:  Ethan A Winkler; Abhay P Sagare; Berislav V Zlokovic
Journal:  Brain Pathol       Date:  2014-07       Impact factor: 6.508

9.  Novel method to study pericyte contractility and responses to ischaemia in vitro using electrical impedance.

Authors:  Ain A Neuhaus; Yvonne Couch; Brad A Sutherland; Alastair M Buchan
Journal:  J Cereb Blood Flow Metab       Date:  2016-01-01       Impact factor: 6.200

10.  Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration.

Authors:  Joanna M Wardlaw; Eric E Smith; Geert J Biessels; Charlotte Cordonnier; Franz Fazekas; Richard Frayne; Richard I Lindley; John T O'Brien; Frederik Barkhof; Oscar R Benavente; Sandra E Black; Carol Brayne; Monique Breteler; Hugues Chabriat; Charles Decarli; Frank-Erik de Leeuw; Fergus Doubal; Marco Duering; Nick C Fox; Steven Greenberg; Vladimir Hachinski; Ingo Kilimann; Vincent Mok; Robert van Oostenbrugge; Leonardo Pantoni; Oliver Speck; Blossom C M Stephan; Stefan Teipel; Anand Viswanathan; David Werring; Christopher Chen; Colin Smith; Mark van Buchem; Bo Norrving; Philip B Gorelick; Martin Dichgans
Journal:  Lancet Neurol       Date:  2013-08       Impact factor: 44.182
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  306 in total

Review 1.  Alzheimer's Disease: The Link Between Amyloid-β and Neurovascular Dysfunction.

Authors:  Ernesto Solis; Kevin N Hascup; Erin R Hascup
Journal:  J Alzheimers Dis       Date:  2020       Impact factor: 4.472

2.  Progressive myoclonic epilepsy-associated gene Kctd7 regulates retinal neurovascular patterning and function.

Authors:  Jonathan Alevy; Courtney A Burger; Nicholas E Albrecht; Danye Jiang; Melanie A Samuel
Journal:  Neurochem Int       Date:  2019-06-06       Impact factor: 3.921

3.  Poster Viewing Sessions PB01-B01 to PB03-V09.

Authors: 
Journal:  J Cereb Blood Flow Metab       Date:  2019-07       Impact factor: 6.200

4.  Neurovascular coupling during optogenetic functional activation: Local and remote stimulus-response characteristics, and uncoupling by spreading depression.

Authors:  Maximilian Böhm; David Y Chung; Carlos A Gómez; Tao Qin; Tsubasa Takizawa; Homa Sadeghian; Kazutaka Sugimoto; Sava Sakadžić; Mohammad A Yaseen; Cenk Ayata
Journal:  J Cereb Blood Flow Metab       Date:  2019-05-07       Impact factor: 6.200

5.  A Pilot Study of Changes in Medial Temporal Lobe Fractional Amplitude of Low Frequency Fluctuations after Sildenafil Administration in Patients with Alzheimer's Disease.

Authors:  Niyatee Samudra; Michael Motes; Hanzhang Lu; Min Sheng; Ramon Diaz-Arrastia; Michael Devous; John Hart; Kyle B Womack
Journal:  J Alzheimers Dis       Date:  2019       Impact factor: 4.472

6.  In vitro models of molecular and nano-particle transport across the blood-brain barrier.

Authors:  Cynthia Hajal; Marco Campisi; Clara Mattu; Valeria Chiono; Roger D Kamm
Journal:  Biomicrofluidics       Date:  2018-05-31       Impact factor: 2.800

7.  Disease Highlights the Cellular Diversity of Neurovascular Units: Sign in Stranger.

Authors:  Frank M Faraci
Journal:  Circ Res       Date:  2017-07-21       Impact factor: 17.367

8.  3D self-organized microvascular model of the human blood-brain barrier with endothelial cells, pericytes and astrocytes.

Authors:  Marco Campisi; Yoojin Shin; Tatsuya Osaki; Cynthia Hajal; Valeria Chiono; Roger D Kamm
Journal:  Biomaterials       Date:  2018-07-12       Impact factor: 12.479

Review 9.  Mechanisms in blood-brain barrier opening and metabolism-challenged cerebrovascular ischemia with emphasis on ischemic stroke.

Authors:  Sajad Sarvari; Faezeh Moakedi; Emily Hone; James W Simpkins; Xuefang Ren
Journal:  Metab Brain Dis       Date:  2020-04-15       Impact factor: 3.584

10.  Age-related impairment of cerebral blood flow response to KATP channel opener in Alzheimer's disease mice with presenilin-1 mutation.

Authors:  Dong Liu; Ismayil Ahmet; Brandon Griess; David Tweedie; Nigel H Greig; Mark P Mattson
Journal:  J Cereb Blood Flow Metab       Date:  2020-11-17       Impact factor: 6.200
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