Literature DB >> 28515090

NF-κB p50 (nfkb1) contributes to pathogenesis in the Eμ-TCL1 mouse model of chronic lymphocytic leukemia.

Timothy L Chen1, Minh Tran1, Aparna Lakshmanan1, Bonnie K Harrington1, Nikhil Gupta1, Virginia M Goettl1, Amy M Lehman2, Stephen Trudeau1, David M Lucas1, Amy J Johnson1, John C Byrd1, Erin Hertlein1.   

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Year:  2017        PMID： 28515090      PMCID： PMC5520469          DOI： 10.1182/blood-2017-01-761130

Source DB:  PubMed          Journal:  Blood        ISSN： 0006-4971            Impact factor:   22.113


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  14 in total

1.  17-DMAG targets the nuclear factor-kappaB family of proteins to induce apoptosis in chronic lymphocytic leukemia: clinical implications of HSP90 inhibition.

Authors:  Erin Hertlein; Amy J Wagner; Jeffrey Jones; Thomas S Lin; Kami J Maddocks; William H Towns; Virginia M Goettl; Xiaoli Zhang; David Jarjoura; Chelsey A Raymond; Derek A West; Carlo M Croce; John C Byrd; Amy J Johnson
Journal:  Blood       Date:  2010-03-29       Impact factor: 22.113

Review 2.  Unravelling the complexities of the NF-kappaB signalling pathway using mouse knockout and transgenic models.

Authors:  S Gerondakis; R Grumont; R Gugasyan; L Wong; I Isomura; W Ho; A Banerjee
Journal:  Oncogene       Date:  2006-10-30       Impact factor: 9.867

3.  Mechanisms of PD-L1/PD-1-mediated CD8 T-cell dysfunction in the context of aging-related immune defects in the Eµ-TCL1 CLL mouse model.

Authors:  Fabienne McClanahan; John C Riches; Shaun Miller; William P Day; Eleni Kotsiou; Donna Neuberg; Carlo M Croce; Melania Capasso; John G Gribben
Journal:  Blood       Date:  2015-05-15       Impact factor: 22.113

4.  Human chronic lymphocytic leukemia modeled in mouse by targeted TCL1 expression.

Authors:  Roberta Bichi; Susan A Shinton; Eric S Martin; Anatoliy Koval; George A Calin; Rossano Cesari; Giandomenico Russo; Richard R Hardy; Carlo M Croce
Journal:  Proc Natl Acad Sci U S A       Date:  2002-05-14       Impact factor: 11.205

5.  p65 activity and ZAP-70 status predict the sensitivity of chronic lymphocytic leukemia cells to the selective IkappaB kinase inhibitor BMS-345541.

Authors:  Mónica López-Guerra; Gaël Roué; Patricia Pérez-Galán; Roberto Alonso; Neus Villamor; Emili Montserrat; Elias Campo; Dolors Colomer
Journal:  Clin Cancer Res       Date:  2009-04-07       Impact factor: 12.531

6.  A Sleeping Beauty screen reveals NF-kB activation in CLL mouse model.

Authors:  Nicola Zanesi; Veronica Balatti; Jesse Riordan; Aaron Burch; Lara Rizzotto; Alexey Palamarchuk; Luciano Cascione; Alessandro Lagana; Adam J Dupuy; Carlo M Croce; Yuri Pekarsky
Journal:  Blood       Date:  2013-04-16       Impact factor: 22.113

7.  Targeted disruption of the p50 subunit of NF-kappa B leads to multifocal defects in immune responses.

Authors:  W C Sha; H C Liou; E I Tuomanen; D Baltimore
Journal:  Cell       Date:  1995-01-27       Impact factor: 41.582

8.  Ibrutinib inhibits BTK-driven NF-κB p65 activity to overcome bortezomib-resistance in multiple myeloma.

Authors:  Megan Y Murray; Lyubov Zaitseva; Martin J Auger; Jenny Io Craig; David J MacEwan; Stuart A Rushworth; Kristian M Bowles
Journal:  Cell Cycle       Date:  2015-01-07       Impact factor: 4.534

9.  Loss of Nfkb1 leads to early onset aging.

Authors:  Giovanna M Bernal; Joshua S Wahlstrom; Clayton D Crawley; Kirk E Cahill; Peter Pytel; Hua Liang; Shijun Kang; Ralph R Weichselbaum; Bakhtiar Yamini
Journal:  Aging (Albany NY)       Date:  2014-11       Impact factor: 5.682

10.  NFκB1 is essential to prevent the development of multiorgan autoimmunity by limiting IL-6 production in follicular B cells.

Authors:  Elisha de Valle; George Grigoriadis; Lorraine A O'Reilly; Simon N Willis; Mhairi J Maxwell; Lynn M Corcoran; Evelyn Tsantikos; Jasper K S Cornish; Kirsten A Fairfax; Ajithkumar Vasanthakumar; Mark A Febbraio; Margaret L Hibbs; Marc Pellegrini; Ashish Banerjee; Philip D Hodgkin; Axel Kallies; Fabienne Mackay; Andreas Strasser; Steve Gerondakis; Raffi Gugasyan
Journal:  J Exp Med       Date:  2016-03-28       Impact factor: 14.307
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  4 in total

Review 1.  New roles for B cell receptor associated kinases: when the B cell is not the target.

Authors:  Phuong-Hien Nguyen; Emanuel Niesen; Michael Hallek
Journal:  Leukemia       Date:  2019-01-30       Impact factor: 11.528

2.  MiR-144-induced KLF2 inhibition and NF-kappaB/CXCR1 activation promote neutrophil extracellular trap-induced transfusion-related acute lung injury.

Authors:  Aiping Le; Yize Wu; Wei Liu; Chenggao Wu; Piaoping Hu; Juan Zou; Linju Kuang
Journal:  J Cell Mol Med       Date:  2021-06-13       Impact factor: 5.310

Review 3.  NFKB1 and Cancer: Friend or Foe?

Authors:  Julia Concetti; Caroline L Wilson
Journal:  Cells       Date:  2018-09-07       Impact factor: 6.600

4.  Biological significance of monoallelic and biallelic BIRC3 loss in del(11q) chronic lymphocytic leukemia progression.

Authors:  José Luis Ordóñez; Jesús-María Hernández-Rivas; Miguel Quijada-Álamo; María Hernández-Sánchez; Ana-Eugenia Rodríguez-Vicente; Claudia Pérez-Carretero; Alberto Rodríguez-Sánchez; Marta Martín-Izquierdo; Verónica Alonso-Pérez; Ignacio García-Tuñón; José María Bastida; María Jesús Vidal-Manceñido; Josefina Galende; Carlos Aguilar; José Antonio Queizán; Isabel González-Gascón Y Marín; José-Ángel Hernández-Rivas; Rocío Benito
Journal:  Blood Cancer J       Date:  2021-07-09       Impact factor: 11.037
  4 in total

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