Literature DB >> 28514684

CD4+ T Cell Activation and Vascular Normalization: Two Sides of the Same Coin?

Michele De Palma1, Rakesh K Jain2.   

Abstract

Normalization of tumor blood vessels enhances the infiltration and functions of T cells. Tian et al. (2017) report that effector CD4+ T cells, in turn, support vascular normalization, highlighting intertwined roles for blood vessels and T cells in cancer.
Copyright © 2017 Elsevier Inc. All rights reserved.

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Year:  2017        PMID： 28514684     DOI： 10.1016/j.immuni.2017.04.015

Source DB:  PubMed          Journal:  Immunity        ISSN： 1074-7613            Impact factor:   31.745


  21 in total

Review 1.  Microenvironmental regulation of tumour angiogenesis.

Authors:  Michele De Palma; Daniela Biziato; Tatiana V Petrova
Journal:  Nat Rev Cancer       Date:  2017-07-14       Impact factor: 60.716

Review 2.  Normalizing Function of Tumor Vessels: Progress, Opportunities, and Challenges.

Authors:  John D Martin; Giorgio Seano; Rakesh K Jain
Journal:  Annu Rev Physiol       Date:  2019-02-10       Impact factor: 19.318

3.  STING activation reprograms tumor vasculatures and synergizes with VEGFR2 blockade.

Authors:  Hannah Yang; Won Suk Lee; So Jung Kong; Chang Gon Kim; Joo Hoon Kim; Sei Kyung Chang; Sewha Kim; Gwangil Kim; Hong Jae Chon; Chan Kim
Journal:  J Clin Invest       Date:  2019-07-25       Impact factor: 14.808

Review 4.  Enhancing cancer immunotherapy using antiangiogenics: opportunities and challenges.

Authors:  Dai Fukumura; Jonas Kloepper; Zohreh Amoozgar; Dan G Duda; Rakesh K Jain
Journal:  Nat Rev Clin Oncol       Date:  2018-03-06       Impact factor: 66.675

5.  N-Glycosylation regulates ligand-dependent activation and signaling of vascular endothelial growth factor receptor 2 (VEGFR2).

Authors:  Kevin Brown Chandler; Deborah R Leon; Jenevieve Kuang; Rosana D Meyer; Nader Rahimi; Catherine E Costello
Journal:  J Biol Chem       Date:  2019-07-15       Impact factor: 5.157

6.  Rapid Depletion of Intratumoral Regulatory T Cells Induces Synchronized CD8 T- and NK-cell Activation and IFNγ-Dependent Tumor Vessel Regression.

Authors:  Yutaka Kurebayashi; Colleen P Olkowski; Kelly C Lane; Olga V Vasalatiy; Biying C Xu; Ryuhei Okada; Aki Furusawa; Peter L Choyke; Hisataka Kobayashi; Noriko Sato
Journal:  Cancer Res       Date:  2021-02-11       Impact factor: 13.312

Review 7.  Synergies of Targeting Tumor Angiogenesis and Immune Checkpoints in Non-Small Cell Lung Cancer and Renal Cell Cancer: From Basic Concepts to Clinical Reality.

Authors:  Andreas Pircher; Dominik Wolf; Axel Heidenreich; Wolfgang Hilbe; Renate Pichler; Isabel Heidegger
Journal:  Int J Mol Sci       Date:  2017-10-31       Impact factor: 5.923

8.  Integrin CD11b activation drives anti-tumor innate immunity.

Authors:  Michael C Schmid; Samia Q Khan; Megan M Kaneda; Paulina Pathria; Ryan Shepard; Tiani L Louis; Sudarshan Anand; Gyunghwi Woo; Chris Leem; M Hafeez Faridi; Terese Geraghty; Anugraha Rajagopalan; Seema Gupta; Mansoor Ahmed; Roberto I Vazquez-Padron; David A Cheresh; Vineet Gupta; Judith A Varner
Journal:  Nat Commun       Date:  2018-12-19       Impact factor: 14.919

Review 9.  Reengineering the Physical Microenvironment of Tumors to Improve Drug Delivery and Efficacy: From Mathematical Modeling to Bench to Bedside.

Authors:  Triantafyllos Stylianopoulos; Lance L Munn; Rakesh K Jain
Journal:  Trends Cancer       Date:  2018-03-13

Review 10.  Antiangiogenic therapy reverses the immunosuppressive breast cancer microenvironment.

Authors:  Wuzhen Chen; Lesang Shen; Jingxin Jiang; Leyi Zhang; Zhigang Zhang; Jun Pan; Chao Ni; Zhigang Chen
Journal:  Biomark Res       Date:  2021-07-22
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