Literature DB >> 28512100

Anaemia and respiratory failure in a child: can it be idiopathic pulmonary haemosiderosis?

Minhajuddin Ahmed, Dinesh Raj1, Ashwini Kumar1, Abhay Kumar1.   

Abstract

We present an 8-year-old male child admitted with cough and high-grade fever for 7 days and respiratory difficulty for 2 days. There was a history of blood transfusion at 2 years of age during a respiratory illness. The child was anaemic, tachycardic, tachypnoeic and hypoxic at presentation. Chest examination revealed equal air entry with fine crackles bilaterally. Blood reports were suggestive of anaemia (haemoglobin 6.5 g/dL), leucocytosis and high C reactive protein levels. Chest radiograph revealed bilateral air space opacities involving diffuse lung fields, right more than left. Relevant microbiological workup was negative. Based on the clinical scenario and investigations, a provisional diagnosis of pulmonary haemosiderosis was kept. The patient was started on intravenous pulse methylprednisolone. Fibre-optic bronchoscopy was done following recovery from the acute event. Bronchoalveolar lavage demonstrated a significant number of haemosiderin-laden macrophages confirming pulmonary haemosiderosis. © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Entities:  

Keywords:  Paediatrics; Respiratory medicine

Mesh:

Substances:

Year:  2017        PMID: 28512100      PMCID: PMC5612269          DOI: 10.1136/bcr-2017-219431

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  8 in total

1.  Screening for celiac disease in idiopathic pulmonary hemosiderosis.

Authors:  M Khemiri; M Ouederni; F Khaldi; S Barsaoui
Journal:  Gastroenterol Clin Biol       Date:  2008-07-07

2.  Idiopathic pulmonary hemosiderosis: clinical profile and follow up of 26 children.

Authors:  S K Kabra; Sumit Bhargava; Rakesh Lodha; A Satyavani; M Walia
Journal:  Indian Pediatr       Date:  2007-05       Impact factor: 1.411

Review 3.  Unexplained childhood anaemia: idiopathic pulmonary hemosiderosis.

Authors:  K K Siu; Rever Li; S Y Lam
Journal:  Hong Kong Med J       Date:  2015-04       Impact factor: 1.256

4.  Benefit of gluten-free diet in idiopathic pulmonary hemosiderosis in association with celiac disease.

Authors:  Gulshan R Sethi; Kamal K Singhal; Amarender S Puri; Mukta Mantan
Journal:  Pediatr Pulmonol       Date:  2010-10-21

5.  New insights into pediatric idiopathic pulmonary hemosiderosis: the French RespiRare(®) cohort.

Authors:  Jessica Taytard; Nadia Nathan; Jacques de Blic; Mickael Fayon; Ralph Epaud; Antoine Deschildre; Françoise Troussier; Marc Lubrano; Raphaël Chiron; Philippe Reix; Pierrick Cros; Malika Mahloul; Delphine Michon; Annick Clement; Harriet Corvol
Journal:  Orphanet J Rare Dis       Date:  2013-10-14       Impact factor: 4.303

6.  Idiopathic Pulmonary Hemosiderosis With Allergic Asthma Diagnosis in a Pediatric Patient.

Authors:  İrem Eldem; Talia İleri; Elif İnce; Fikret Asarcikli; Esra Pekpak; Hasan F Çakmakli; Koray Ceyhan; Zümrüt Uysal
Journal:  J Pediatr Hematol Oncol       Date:  2015-10       Impact factor: 1.170

7.  Idiopathic Pulmonary Hemosiderosis Presenting as Anemia, Failure to Thrive, and Jaundice in a Toddler.

Authors:  Carol C Chen; Julie K McManemy; Timothy J Vece; Andrea T Cruz
Journal:  Pediatr Emerg Care       Date:  2016-04       Impact factor: 1.602

8.  Idiopathic pulmonary hemosiderosis - a diagnostic challenge.

Authors:  Ilirjana Bakalli; Luljeta Kota; Durim Sala; Ermela Celaj; Elmira Kola; Robert Lluka; Sashenka Sallabanda
Journal:  Ital J Pediatr       Date:  2014-04-04       Impact factor: 3.288

  8 in total

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