Literature DB >> 28511815

Signature of the Sleeper Cell: A Biomarker of HIV Latency Revealed.

Satish K Pillai1, Steven G Deeks2.   

Abstract

HIV establishes a reservoir in latently infected T cells, and this reservoir has long hampered curative approaches. A recent study by Descours et al. identifies CD32a as a marker of latently infected T cells, potentially opening the way to the development of strategies that directly target this critical HIV reservoir.
Copyright © 2017 Elsevier Ltd. All rights reserved.

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Year:  2017        PMID： 28511815      PMCID： PMC6091624          DOI： 10.1016/j.it.2017.04.007

Source DB:  PubMed          Journal:  Trends Immunol        ISSN： 1471-4906            Impact factor:   16.687


  10 in total

Review 1.  Fcgamma receptors as regulators of immune responses.

Authors:  Falk Nimmerjahn; Jeffrey V Ravetch
Journal:  Nat Rev Immunol       Date:  2008-01       Impact factor: 53.106

2.  HIV: Shock and kill.

Authors:  Steven G Deeks
Journal:  Nature       Date:  2012-07-25       Impact factor: 49.962

3.  Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy.

Authors:  D Finzi; M Hermankova; T Pierson; L M Carruth; C Buck; R E Chaisson; T C Quinn; K Chadwick; J Margolick; R Brookmeyer; J Gallant; M Markowitz; D D Ho; D D Richman; R F Siliciano
Journal:  Science       Date:  1997-11-14       Impact factor: 47.728

4.  CD32a is a marker of a CD4 T-cell HIV reservoir harbouring replication-competent proviruses.

Authors:  Benjamin Descours; Gaël Petitjean; José-Luis López-Zaragoza; Timothée Bruel; Raoul Raffel; Christina Psomas; Jacques Reynes; Christine Lacabaratz; Yves Levy; Olivier Schwartz; Jean Daniel Lelievre; Monsef Benkirane
Journal:  Nature       Date:  2017-03-15       Impact factor: 49.962

5.  Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation.

Authors:  Gero Hütter; Daniel Nowak; Maximilian Mossner; Susanne Ganepola; Arne Müssig; Kristina Allers; Thomas Schneider; Jörg Hofmann; Claudia Kücherer; Olga Blau; Igor W Blau; Wolf K Hofmann; Eckhard Thiel
Journal:  N Engl J Med       Date:  2009-02-12       Impact factor: 91.245

6.  Recovery of replication-competent HIV despite prolonged suppression of plasma viremia.

Authors:  J K Wong; M Hezareh; H F Günthard; D V Havlir; C C Ignacio; C A Spina; D D Richman
Journal:  Science       Date:  1997-11-14       Impact factor: 47.728

7.  CD4+ T Cells Expressing PD-1, TIGIT and LAG-3 Contribute to HIV Persistence during ART.

Authors:  Rémi Fromentin; Wendy Bakeman; Mariam B Lawani; Gabriela Khoury; Wendy Hartogensis; Sandrina DaFonseca; Marisela Killian; Lorrie Epling; Rebecca Hoh; Elizabeth Sinclair; Frederick M Hecht; Peter Bacchetti; Steven G Deeks; Sharon R Lewin; Rafick-Pierre Sékaly; Nicolas Chomont
Journal:  PLoS Pathog       Date:  2016-07-14       Impact factor: 6.823

8.  Replication-competent noninduced proviruses in the latent reservoir increase barrier to HIV-1 cure.

Authors:  Ya-Chi Ho; Liang Shan; Nina N Hosmane; Jeffrey Wang; Sarah B Laskey; Daniel I S Rosenbloom; Jun Lai; Joel N Blankson; Janet D Siliciano; Robert F Siliciano
Journal:  Cell       Date:  2013-10-24       Impact factor: 41.582

9.  Follicular helper T cells serve as the major CD4 T cell compartment for HIV-1 infection, replication, and production.

Authors:  Matthieu Perreau; Anne-Laure Savoye; Elisa De Crignis; Jean-Marc Corpataux; Rafael Cubas; Elias K Haddad; Laurence De Leval; Cecilia Graziosi; Giuseppe Pantaleo
Journal:  J Exp Med       Date:  2012-12-17       Impact factor: 14.307

10.  SAMHD1 restricts HIV-1 reverse transcription in quiescent CD4(+) T-cells.

Authors:  Benjamin Descours; Alexandra Cribier; Christine Chable-Bessia; Diana Ayinde; Gillian Rice; Yanick Crow; Ahmad Yatim; Olivier Schwartz; Nadine Laguette; Monsef Benkirane
Journal:  Retrovirology       Date:  2012-10-23       Impact factor: 4.602
  10 in total
  4 in total

Review 1.  Differentiating Immune Cell Targets in Gut-Associated Lymphoid Tissue for HIV Cure.

Authors:  Shahzada Khan; Sushama Telwatte; Martin Trapecar; Steven Yukl; Shomyseh Sanjabi
Journal:  AIDS Res Hum Retroviruses       Date:  2017-11       Impact factor: 2.205

2.  CD32-RNA Co-localizes with HIV-RNA in CD3+ Cells Found within Gut Tissues from Viremic and ART-Suppressed Individuals.

Authors:  Joshua J Vásquez; Brandon L Aguilar-Rodriguez; Leonardo Rodriguez; Louise E Hogan; Ma Somsouk; Joseph M McCune; Steven G Deeks; Zoltan G Laszik; Peter W Hunt; Timothy J Henrich
Journal:  Pathog Immun       Date:  2019-05-03

Review 3.  The Quest for Cellular Markers of HIV Reservoirs: Any Color You Like.

Authors:  Gilles Darcis; Ben Berkhout; Alexander O Pasternak
Journal:  Front Immunol       Date:  2019-09-20       Impact factor: 7.561

4.  CD32 expression is associated to T-cell activation and is not a marker of the HIV-1 reservoir.

Authors:  Roger Badia; Ester Ballana; Marc Castellví; Edurne García-Vidal; Maria Pujantell; Bonaventura Clotet; Julia G Prado; Jordi Puig; Miguel A Martínez; Eva Riveira-Muñoz; José A Esté
Journal:  Nat Commun       Date:  2018-07-16       Impact factor: 14.919
  4 in total

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