Literature DB >> 28511478

Recognition of Small Airways Obstruction in Asthma and COPD - The Road Less Travelled.

Desh Deepak1, Akhila Prasad2, Swapndeep Singh Atwal3, Kshitij Agarwal4.   

Abstract

The small airways, once regarded as the silent zone in the air conducting system of the lungs are now known to be one of the initial sites of involvement in diseases like asthma and Chronic Obstructive Pulmonary Disease (COPD). Identification of the involvement of distal airways in these diseases is often difficult to assess, clinically as well as by conventional pulmonary function tests and therefore, usually remains undiscovered in early stages. Early recognition of their involvement in asthma and COPD and timely management may reduce long term morbidity in these conditions. This article aims to highlight the relatively lesser recognized facts about small airways involvement in asthma and COPD and role of imaging and newer modalities for detection.

Entities:  

Keywords:  High resolution computed tomography; Mosaic attenuation; Pulmonary function tests

Year:  2017        PMID: 28511478      PMCID: PMC5427404          DOI: 10.7860/JCDR/2017/19920.9478

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  26 in total

1.  Air trapping in mild and moderate asthma: effect of inhaled corticosteroids.

Authors:  José-Manuel Tunon-de-Lara; François Laurent; Violaine Giraud; Thierry Perez; Bernard Aguilaniu; Houari Meziane; Armelle Basset-Merle; Pascal Chanez
Journal:  J Allergy Clin Immunol       Date:  2007-01-03       Impact factor: 10.793

Review 2.  The small airways and distal lung compartment in asthma and COPD: a time for reappraisal.

Authors:  M Contoli; J Bousquet; L M Fabbri; H Magnussen; K F Rabe; N M Siafakas; Q Hamid; M Kraft
Journal:  Allergy       Date:  2009-11-11       Impact factor: 13.146

Review 3.  The role of small airways in obstructive airway diseases.

Authors:  P-R Burgel
Journal:  Eur Respir Rev       Date:  2011-03

4.  COPD: the unrecognized epidemic in India.

Authors:  S K Jindal
Journal:  J Assoc Physicians India       Date:  2012-02

Review 5.  Unlocking the quiet zone: the small airway asthma phenotype.

Authors:  Brian Lipworth; Arvind Manoharan; William Anderson
Journal:  Lancet Respir Med       Date:  2014-06       Impact factor: 30.700

6.  Comparative effects of hydrofluoroalkane and chlorofluorocarbon beclomethasone dipropionate inhalation on small airways: assessment with functional helical thin-section computed tomography.

Authors:  J G Goldin; D P Tashkin; E C Kleerup; L E Greaser; U M Haywood; J W Sayre; M D Simmons; M Suttorp; G L Colice; J A Vanden Burgt; D R Aberle
Journal:  J Allergy Clin Immunol       Date:  1999-12       Impact factor: 10.793

7.  Effects of inhaled corticosteroids with different lung deposition on exhaled hydrogen peroxide in stable COPD patients.

Authors:  W J C van Beurden; G A Harff; P N R Dekhuijzen; S M van der Poel-Smet; F W J M Smeenk
Journal:  Respiration       Date:  2003 May-Jun       Impact factor: 3.580

8.  A multivariate analysis of risk factors for the air-trapping asthmatic phenotype as measured by quantitative CT analysis.

Authors:  Ashley Busacker; John D Newell; Thomas Keefe; Eric A Hoffman; Janice Cook Granroth; Mario Castro; Sean Fain; Sally Wenzel
Journal:  Chest       Date:  2008-08-08       Impact factor: 9.410

Review 9.  Small airways dysfunction in asthma: evaluation and management to improve asthma control.

Authors:  Omar S Usmani
Journal:  Allergy Asthma Immunol Res       Date:  2014-06-18       Impact factor: 5.764

Review 10.  Techniques of assessing small airways dysfunction.

Authors:  William McNulty; Omar S Usmani
Journal:  Eur Clin Respir J       Date:  2014-10-17
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  5 in total

1.  Fibrinogen mediates cadmium-induced macrophage activation and serves as a predictor of cadmium exposure in chronic obstructive pulmonary disease.

Authors:  Fu Jun Li; Ranu Surolia; Pooja Singh; Kevin G Dsouza; Crystal T Stephens; Zheng Wang; Rui-Ming Liu; Sejong Bae; Young-Il Kim; Mohammad Athar; Mark T Dransfield; Veena B Antony
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2022-02-24       Impact factor: 5.464

2.  The disconnect between visual assessment of air trapping and lung physiology for assessment of small airway disease in scleroderma-related interstitial lung disease: An observation from the Scleroderma Lung Study II Cohort.

Authors:  Sangmee Sharon Bae; Lila Pourzand; Grace Hyun Kim; Bianca E Villegas; Andrea Oh; Daniel E Furst; Jonathan Goldin; Donald P Tashkin
Journal:  J Scleroderma Relat Disord       Date:  2021-10-23

Review 3.  Small Airways, Big Problem: Extrafine beclomethasone/formoterol in asthma and chronic obstructive pulmonary disease.

Authors:  Ashfaq Hasan; Priyanka Mukherjee; Sushmeeta Chhowala; Meena Lopez; Prashant N Chhajed
Journal:  Lung India       Date:  2021 Jul-Aug

4.  Crocin attenuates cigarette smoke-induced lung injury and cardiac dysfunction by anti-oxidative effects: the role of Nrf2 antioxidant system in preventing oxidative stress.

Authors:  Mahin Dianat; Maryam Radan; Mohammad Badavi; Seyyed Ali Mard; Vahid Bayati; Masoumeh Ahmadizadeh
Journal:  Respir Res       Date:  2018-04-10

5.  FEF25-75% Values in Patients with Normal Lung Function Can Predict the Development of Chronic Obstructive Pulmonary Disease.

Authors:  Do Sun Kwon; Yong Jun Choi; Tae Hee Kim; Min Kwang Byun; Jae Hwa Cho; Hyung Jung Kim; Hye Jung Park
Journal:  Int J Chron Obstruct Pulmon Dis       Date:  2020-11-12
  5 in total

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