Literature DB >> 2851122

Detection and characterization of the protein encoded by the chicken c-rel protooncogene.

S Simek1, N R Rice.   

Abstract

We have identified the protein encoded by chicken c-rel, the cellular homolog of the v-rel oncogene carried by reticuloendotheliosis virus. The protein has been detected in two avian lymphoid cell lines and in chick embryo fibroblasts. It has a molecular weight of 68,000, suggesting that the viral gene (which encodes a protein of 59,000 molecular weight) is a truncated form of its cellular homolog. The c-rel protein is found in the soluble cytoplasmic fraction of chicken lymphoid cells and is not associated in any stable way with other cellular proteins. Unlike the viral protein, p68c-rel is not detectably phosphorylated.

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Year:  1988        PMID： 2851122

Source DB:  PubMed          Journal:  Oncogene Res        ISSN： 0890-6467


  15 in total

1.  A protein kinase-A recognition sequence is structurally linked to transformation by p59v-rel and cytoplasmic retention of p68c-rel.

Authors:  G Mosialos; P Hamer; A J Capobianco; R A Laursen; T D Gilmore
Journal:  Mol Cell Biol       Date:  1991-12       Impact factor: 4.272

2.  vRel is an inactive member of the Rel family of transcriptional activating proteins.

Authors:  P M Richardson; T D Gilmore
Journal:  J Virol       Date:  1991-06       Impact factor: 5.103

3.  Avian reticuloendotheliosis virus-transformed lymphoid cells contain multiple pp59v-rel complexes.

Authors:  N Davis; W Bargmann; M Y Lim; H Bose
Journal:  J Virol       Date:  1990-02       Impact factor: 5.103

4.  Transactivation of gene expression by nuclear and cytoplasmic rel proteins.

Authors:  M Hannink; H M Temin
Journal:  Mol Cell Biol       Date:  1989-10       Impact factor: 4.272

5.  Casein kinase II phosphorylates I kappa B alpha at S-283, S-289, S-293, and T-291 and is required for its degradation.

Authors:  J A McElhinny; S A Trushin; G D Bren; N Chester; C V Paya
Journal:  Mol Cell Biol       Date:  1996-03       Impact factor: 4.272

6.  Identification of a rel-related protein in the nucleus during the S phase of the cell cycle.

Authors:  R B Evans; P D Gottlieb; H R Bose
Journal:  Mol Cell Biol       Date:  1993-10       Impact factor: 4.272

7.  p59v-rel, the transforming protein of reticuloendotheliosis virus, is complexed with at least four other proteins in transformed chicken lymphoid cells.

Authors:  S Simek; N R Rice
Journal:  J Virol       Date:  1988-12       Impact factor: 5.103

8.  p105, the NF-kappa B p50 precursor protein, is one of the cellular proteins complexed with the v-Rel oncoprotein in transformed chicken spleen cells.

Authors:  A J Capobianco; D Chang; G Mosialos; T D Gilmore
Journal:  J Virol       Date:  1992-06       Impact factor: 5.103

9.  Regulation of I kappa B alpha and p105 in monocytes and macrophages persistently infected with human immunodeficiency virus.

Authors:  J A McElhinny; W S MacMorran; G D Bren; R M Ten; A Israel; C V Paya
Journal:  J Virol       Date:  1995-03       Impact factor: 5.103

10.  Development of Foxp3(+) regulatory t cells is driven by the c-Rel enhanceosome.

Authors:  Qingguo Ruan; Vasumathi Kameswaran; Yukiko Tone; Li Li; Hsiou-Chi Liou; Mark I Greene; Masahide Tone; Youhai H Chen
Journal:  Immunity       Date:  2009-12-18       Impact factor: 31.745
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