Literature DB >> 28509116

Tonic regulation of stationary asynchronous firing of a neural network.

D A Adamchik1, V B Kazantsev2.   

Abstract

The impact of tonic conductance upon population activity was investigated. An extra tonic transmembrane current through GABA-activated extrasynaptic GABA A -receptors was found to control stationary asynchronous firing both quantitatively and qualitatively. Quantitative regulation consisted in alterating a current level of stationary population activity while qualitative regulation manifested itself in appearance of resilient asynchronous spiking in case GABA reversal potential exceeded a certain threshold. The study was based on a modified rate model after Wilson and Cowan and backed up with a computer simulation of an explicit network model.

Entities:  

Keywords:  Asynchronous firing; GABA; Rate model; Tonic conductance

Mesh：

Substances：

Year:  2017        PMID： 28509116     DOI： 10.1007/s10827-017-0648-6

Source DB:  PubMed          Journal:  J Comput Neurosci        ISSN： 0929-5313            Impact factor:   1.621


  10 in total

1.  Tonically activated GABAA receptors in hippocampal neurons are high-affinity, low-conductance sensors for extracellular GABA.

Authors:  Jacky Y T Yeung; Kevin J Canning; Guoyun Zhu; Peter Pennefather; John F MacDonald; Beverley A Orser
Journal:  Mol Pharmacol       Date:  2003-01       Impact factor: 4.436

2.  Turning on and off recurrent balanced cortical activity.

Authors:  Yousheng Shu; Andrea Hasenstaub; David A McCormick
Journal:  Nature       Date:  2003-05-15       Impact factor: 49.962

Review 3.  Tonically active GABA A receptors: modulating gain and maintaining the tone.

Authors:  Alexey Semyanov; Matthew C Walker; Dimitri M Kullmann; R Angus Silver
Journal:  Trends Neurosci       Date:  2004-05       Impact factor: 13.837

4.  Shunting inhibition improves robustness of gamma oscillations in hippocampal interneuron networks by homogenizing firing rates.

Authors:  Imre Vida; Marlene Bartos; Peter Jonas
Journal:  Neuron       Date:  2006-01-05       Impact factor: 17.173

Review 5.  Activation of GABAA receptors: views from outside the synaptic cleft.

Authors:  Joseph Glykys; Istvan Mody
Journal:  Neuron       Date:  2007-12-06       Impact factor: 17.173

6.  Gamma oscillation by synaptic inhibition in a hippocampal interneuronal network model.

Authors:  X J Wang; G Buzsáki
Journal:  J Neurosci       Date:  1996-10-15       Impact factor: 6.167

7.  A mathematical theory of the functional dynamics of cortical and thalamic nervous tissue.

Authors:  H R Wilson; J D Cowan
Journal:  Kybernetik       Date:  1973-09

8.  GABA transporter deficiency causes tremor, ataxia, nervousness, and increased GABA-induced tonic conductance in cerebellum.

Authors:  Chi-Sung Chiu; Stephen Brickley; Kimmo Jensen; Amber Southwell; Sheri Mckinney; Stuart Cull-Candy; Istvan Mody; Henry A Lester
Journal:  J Neurosci       Date:  2005-03-23       Impact factor: 6.167

9.  Tonic GABAA conductance bidirectionally controls interneuron firing pattern and synchronization in the CA3 hippocampal network.

Authors:  Ivan Pavlov; Leonid P Savtchenko; Inseon Song; Jaeyeon Koo; Alexey Pimashkin; Dmitri A Rusakov; Alexey Semyanov
Journal:  Proc Natl Acad Sci U S A       Date:  2013-12-16       Impact factor: 11.205

10.  Tonic excitation or inhibition is set by GABA(A) conductance in hippocampal interneurons.

Authors:  Inseon Song; Leonid Savtchenko; Alexey Semyanov
Journal:  Nat Commun       Date:  2011-07-05       Impact factor: 14.919
  10 in total
  1 in total

1.  Emergence of Relaxation Oscillations in Neurons Interacting With Non-stationary Ambient GABA.

Authors:  Denis A Adamchik; Valery V Matrosov; Victor B Kazantsev
Journal:  Front Comput Neurosci       Date:  2018-04-05       Impact factor: 2.380
  1 in total

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