Literature DB >> 28508913

Digitally encoded silica microparticles for multiplexed nucleic acid detection.

Weiwei Xu1, Chao Chen, Xiaodong Ma, Lihua Yuan, Shenquan Liu, Kexiao Zheng, Jiong Li.   

Abstract

A robust high throughput suspension array was proposed to analyze biomolecules. To exploit its capacity for nucleic acid detection, we designed a multiplex nested asymmetric PCR (MNAS PCR) that can produce single stranded DNA (ssDNA) efficiently without complicated optimization. Multiplexed HPV genotyping was demonstrated with high selectivity, high sensitivity and rapid hybridization within 20 minutes.

Entities:  

Mesh:

Substances:

Year:  2017        PMID: 28508913     DOI: 10.1039/c7cc01974b

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  1 in total

1.  Thermodynamics and kinetics guided probe design for uniformly sensitive and specific DNA hybridization without optimization.

Authors:  Xin Chen; Na Liu; Liquan Liu; Wei Chen; Na Chen; Meng Lin; Jiaju Xu; Xing Zhou; Hongbo Wang; Meiping Zhao; Xianjin Xiao
Journal:  Nat Commun       Date:  2019-10-14       Impact factor: 14.919

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.