Literature DB >> 28508905

An eco-friendly in situ activatable antibiotic via cucurbit[8]uril-mediated supramolecular crosslinking of branched polyethylenimine.

Shengke Li1, Nan Jiang, Wenxuan Zhao, Yuan-Fu Ding, Ying Zheng, Lian-Hui Wang, Jun Zheng, Ruibing Wang.   

Abstract

We report an unprecedented, eco-friendly, in situ activatable model antibiotic, phenylalanyl-polyethylenimine (PhePEI), to potentially diminish antibiotic pollution of the environment and associated antibiotic resistance. The inactive PhePEI can be reversibly activated upon supramolecular crosslinking by cucurbit[8]uril, conferring potent antibacterial activity.

Entities:  

Year:  2017        PMID： 28508905     DOI： 10.1039/c7cc02466e

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  6 in total

1.  On-Resin Recognition of Aromatic Oligopeptides and Proteins through Host-Enhanced Heterodimerization.

Authors:  Xiaoyi Chen; Zehuan Huang; Renata L Sala; Alan M McLean; Guanglu Wu; Kamil Sokołowski; Katie King; Jade A McCune; Oren A Scherman
Journal:  J Am Chem Soc       Date:  2022-05-10       Impact factor: 16.383

Review 2.  Applications of Cucurbiturils in Medicinal Chemistry and Chemical Biology.

Authors:  Debapratim Das; Khaleel I Assaf; Werner M Nau
Journal:  Front Chem       Date:  2019-09-13       Impact factor: 5.221

3.  Host-guest interactions in nor-seco-cucurbit[10]uril: novel guest-dependent molecular recognition and stereoisomerism.

Authors:  Xiaodong Zhang; Wei Wu; Zhu Tao; Xin-Long Ni
Journal:  Beilstein J Org Chem       Date:  2019-07-19       Impact factor: 2.883

4.  Regulation of Antimicrobial Effect of Hemicyanine-Based Photosensitizer via Supramolecular Assembly.

Authors:  Huanxiang Yuan; Shaochuan Jia; Zelin Li; Jian Liu; Xiaoyu Wang; Ruilian Qi
Journal:  Nanomaterials (Basel)       Date:  2022-08-24       Impact factor: 5.719

Review 5.  Cucurbit[8]uril-based supramolecular hydrogels for biomedical applications.

Authors:  Zeyu Wang; Mingju Shui; Ian W Wyman; Qing-Wen Zhang; Ruibing Wang
Journal:  RSC Med Chem       Date:  2021-03-10

6.  Assessment of the Biocompatibility of Cucurbiturils in Blood Cells.

Authors:  Alina Aktanova; Tatjana Abramova; Ekaterina Pashkina; Olga Boeva; Lyubov Grishina; Ekaterina Kovalenko; Vladimir Kozlov
Journal:  Nanomaterials (Basel)       Date:  2021-05-21       Impact factor: 5.076
  6 in total

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