| Literature DB >> 2850785 |
C H Kocken1, H J Geerligs, C A Bos, G Ab, W J Weijer, J W Drijfhout, G W Welling, S Welling-Wester.
Abstract
The N-terminal fragment, comprising residues -5 to 55 of herpes simplex virus type 1 glycoprotein D was expressed as a beta-galactosidase fusion protein in Escherichia coli. This gD-fusion protein reacts with monoclonal antibody LP 14 directed against glycoprotein D of HSV. Antisera obtained after immunization of rabbits with purified gD-fusion protein react with HSV-1 gD in a Western blot and with N-terminal synthetic peptides of gD. In addition, these antisera are able to neutralize viral infectivity in vitro.Entities:
Mesh:
Substances:
Year: 1988 PMID: 2850785 DOI: 10.1007/bf01311098
Source DB: PubMed Journal: Arch Virol ISSN: 0304-8608 Impact factor: 2.574