Literature DB >> 28507020

TGF-β Family Signaling in Mesenchymal Differentiation.

Ingo Grafe1, Stefanie Alexander1, Jonathan R Peterson2, Taylor Nicholas Snider3, Benjamin Levi2, Brendan Lee1, Yuji Mishina3.   

Abstract

Mesenchymal stem cells (MSCs) can differentiate into several lineages during development and also contribute to tissue homeostasis and regeneration, although the requirements for both may be distinct. MSC lineage commitment and progression in differentiation are regulated by members of the transforming growth factor-β (TGF-β) family. This review focuses on the roles of TGF-β family signaling in mesenchymal lineage commitment and differentiation into osteoblasts, chondrocytes, myoblasts, adipocytes, and tenocytes. We summarize the reported findings of cell culture studies, animal models, and interactions with other signaling pathways and highlight how aberrations in TGF-β family signaling can drive human disease by affecting mesenchymal differentiation.
Copyright © 2018 Cold Spring Harbor Laboratory Press; all rights reserved.

Entities:  

Mesh：

Substances：

Year:  2018        PMID： 28507020      PMCID： PMC5932590          DOI： 10.1101/cshperspect.a022202

Source DB:  PubMed          Journal:  Cold Spring Harb Perspect Biol        ISSN： 1943-0264            Impact factor:   10.005


  533 in total

1.  Extracellular matrix-associated bone morphogenetic proteins are essential for differentiation of murine osteoblastic cells in vitro.

Authors:  M Suzawa; Y Takeuchi; S Fukumoto; S Kato; N Ueno; K Miyazono; T Matsumoto; T Fujita
Journal:  Endocrinology       Date:  1999-05       Impact factor: 4.736

2.  Role of PPARgamma in regulating a cascade expression of cyclin-dependent kinase inhibitors, p18(INK4c) and p21(Waf1/Cip1), during adipogenesis.

Authors:  R F Morrison; S R Farmer
Journal:  J Biol Chem       Date:  1999-06-11       Impact factor: 5.157

3.  Assignment of transforming growth factor beta1 and beta3 and a third new ligand to the type I receptor ALK-1.

Authors:  A Lux; L Attisano; D A Marchuk
Journal:  J Biol Chem       Date:  1999-04-09       Impact factor: 5.157

4.  Parathyroid hormone-related peptide (PTHrP)-dependent and -independent effects of transforming growth factor beta (TGF-beta) on endochondral bone formation.

Authors:  R Serra; A Karaplis; P Sohn
Journal:  J Cell Biol       Date:  1999-05-17       Impact factor: 10.539

5.  Multilineage potential of adult human mesenchymal stem cells.

Authors:  M F Pittenger; A M Mackay; S C Beck; R K Jaiswal; R Douglas; J D Mosca; M A Moorman; D W Simonetti; S Craig; D R Marshak
Journal:  Science       Date:  1999-04-02       Impact factor: 47.728

6.  Effects of bone morphogenetic protein-2 on human neonatal calvaria cell differentiation.

Authors:  E Hay; M Hott; A M Graulet; A Lomri; P J Marie
Journal:  J Cell Biochem       Date:  1999-01-01       Impact factor: 4.429

7.  The role of SF/HGF and c-Met in the development of skeletal muscle.

Authors:  S Dietrich; F Abou-Rebyeh; H Brohmann; F Bladt; E Sonnenberg-Riethmacher; T Yamaai; A Lumsden; B Brand-Saberi; C Birchmeier
Journal:  Development       Date:  1999-04       Impact factor: 6.868

8.  Control of digit formation by activin signalling.

Authors:  R Merino; D Macias; Y Gañan; J Rodriguez-Leon; A N Economides; C Rodriguez-Esteban; J C Izpisua-Belmonte; J M Hurle
Journal:  Development       Date:  1999-05       Impact factor: 6.868

9.  Mechanisms of GDF-5 action during skeletal development.

Authors:  P H Francis-West; A Abdelfattah; P Chen; C Allen; J Parish; R Ladher; S Allen; S MacPherson; F P Luyten; C W Archer
Journal:  Development       Date:  1999-03       Impact factor: 6.868

10.  Reduced differentiation potential of primary MyoD-/- myogenic cells derived from adult skeletal muscle.

Authors:  L A Sabourin; A Girgis-Gabardo; P Seale; A Asakura; M A Rudnicki
Journal:  J Cell Biol       Date:  1999-02-22       Impact factor: 10.539
View more
  57 in total

1.  Distinctive role of ACVR1 in dentin formation: requirement for dentin thickness in molars and prevention of osteodentin formation in incisors of mice.

Authors:  Xue Zhang; Ce Shi; Huan Zhao; Yijun Zhou; Yue Hu; Guangxing Yan; Cangwei Liu; Daowei Li; Xinqing Hao; Yuji Mishina; Qilin Liu; Hongchen Sun
Journal:  J Mol Histol       Date:  2018-12-05       Impact factor: 2.611

2.  Activin A receptor type 1-mediated BMP signaling regulates RANKL-induced osteoclastogenesis via canonical SMAD-signaling pathway.

Authors:  Maiko Omi; Vesa Kaartinen; Yuji Mishina
Journal:  J Biol Chem       Date:  2019-10-16       Impact factor: 5.157

3.  Role of MSC-derived galectin 3 in the AML microenvironment.

Authors:  Peter P Ruvolo; Vivian R Ruvolo; Jared K Burks; YiHua Qiu; Rui-Yu Wang; Elizabeth J Shpall; Leonardo Mirandola; Numsen Hail; Zhihong Zeng; Teresa McQueen; Naval Daver; Sean M Post; Maurizio Chiriva-Internati; Steven M Kornblau; Michael Andreeff
Journal:  Biochim Biophys Acta Mol Cell Res       Date:  2018-04-12       Impact factor: 4.739

Review 4.  Specificity, versatility, and control of TGF-β family signaling.

Authors:  Rik Derynck; Erine H Budi
Journal:  Sci Signal       Date:  2019-02-26       Impact factor: 8.192

5.  Transforming growth factor-β (TGF-β)-induced up-regulation of TGF-β receptors at the cell surface amplifies the TGF-β response.

Authors:  Dana Duan; Rik Derynck
Journal:  J Biol Chem       Date:  2019-04-04       Impact factor: 5.157

6.  Asporin Restricts Mesenchymal Stromal Cell Differentiation, Alters the Tumor Microenvironment, and Drives Metastatic Progression.

Authors:  Robert M Hughes; Brian W Simons; Hamda Khan; Rebecca Miller; Valentina Kugler; Samantha Torquato; Debebe Theodros; Michael C Haffner; Tamara Lotan; Jessie Huang; Elai Davicioni; Steven S An; Ryan C Riddle; Daniel L J Thorek; Isla P Garraway; Elana J Fertig; John T Isaacs; W Nathaniel Brennen; Ben H Park; Paula J Hurley
Journal:  Cancer Res       Date:  2019-05-23       Impact factor: 12.701

7.  Augmented BMP signaling commits cranial neural crest cells to a chondrogenic fate by suppressing autophagic β-catenin degradation.

Authors:  Jingwen Yang; Megumi Kitami; Haichun Pan; Masako Toda Nakamura; Honghao Zhang; Fei Liu; Lingxin Zhu; Yoshihiro Komatsu; Yuji Mishina
Journal:  Sci Signal       Date:  2021-01-12       Impact factor: 8.192

8.  The regulatory protein SnoN antagonizes activin/Smad2 protein signaling and thereby promotes adipocyte differentiation and obesity in mice.

Authors:  Qingwei Zhu; Amanda Chang; Albert Xu; Kunxin Luo
Journal:  J Biol Chem       Date:  2018-07-20       Impact factor: 5.157

Review 9.  Energy metabolism: A newly emerging target of BMP signaling in bone homeostasis.

Authors:  Jingwen Yang; Hiroki Ueharu; Yuji Mishina
Journal:  Bone       Date:  2020-06-05       Impact factor: 4.398

Review 10.  Sinking Our Teeth in Getting Dental Stem Cells to Clinics for Bone Regeneration.

Authors:  Sarah Hani Shoushrah; Janis Lisa Transfeld; Christian Horst Tonk; Dominik Büchner; Steffen Witzleben; Martin A Sieber; Margit Schulze; Edda Tobiasch
Journal:  Int J Mol Sci       Date:  2021-06-15       Impact factor: 5.923
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.