Literature DB >> 2850404

[Manifestation of Gilbert syndrome (Meulengracht disease) following orthotopic liver transplantation: a rare cause of postoperative hyperbilirubinemia].

D Henne-Bruns1, B Kremer.   

Abstract

In a 33 years old woman an orthotopic liver transplantation was performed because of an endstage posthepatic liver cirrhosis. Postoperatively the unconjugated bilirubin levels remained elevated although liver enzyme values were within normal range. Because hemolysis, rejection, infection or biliary obstruction could be excluded we suspected a Gilbert's Syndrome and were able to confirm this diagnosis by low caloric intake and nicotinic acid test. This case report therefore describes the first time the transplantation of a clinically harmless metabolic disorder but inborn error of metabolism by liver grafting into the recipient.

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Year:  1988        PMID: 2850404     DOI: 10.1007/bf01720835

Source DB:  PubMed          Journal:  Klin Wochenschr        ISSN: 0023-2173


  11 in total

1.  Effect of dietary composition on the unconjugated hyperbilirubinaemia of Gilbert's syndrome.

Authors:  J L Gollan; C Bateman; B H Billing
Journal:  Gut       Date:  1976-05       Impact factor: 23.059

Review 2.  Current concepts of bilirubin metabolism and hereditary hyperbilirubinemia.

Authors:  B F Scharschmidt; J L Gollan
Journal:  Prog Liver Dis       Date:  1979

3.  Diagnosis of Gilbert's syndrome: role of reduced caloric intake test.

Authors:  D Owens; S Sherlock
Journal:  Br Med J       Date:  1973-09-15

4.  Late mortality and morbidity after liver transplantation.

Authors:  S Iwatsuki; T E Starzl; R D Gordon; C O Esquivel; S Todo; A G Tzakis; L Makowka; J W Marsh; C M Miller
Journal:  Transplant Proc       Date:  1987-02       Impact factor: 1.066

5.  Liver disorders in children: the indications for liver replacement in parenchymal and metabolic diseases.

Authors:  A P Mowat
Journal:  Transplant Proc       Date:  1987-08       Impact factor: 1.066

6.  Hepatic transplantation in Europe. First Report of the European Liver Transplant Registry.

Authors:  H Bismuth; D Castaing; B G Ericzon; J B Otte; K Rolles; B Ringe; M Sloof
Journal:  Lancet       Date:  1987-09-19       Impact factor: 79.321

7.  The nicotinic acid test in constitutional conjugated hyperbilirubinemias and effects of corticosteroid.

Authors:  H Ohkubo; K Okuda
Journal:  Hepatology       Date:  1984 Nov-Dec       Impact factor: 17.425

8.  Studies on nicotinic acid interaction with bilirubin metabolism.

Authors:  H Ohkubo; H Musha; K Okuda
Journal:  Dig Dis Sci       Date:  1979-09       Impact factor: 3.199

Review 9.  Constitutional hepatic dysfunction (CHD; Gilbert's disease); a review with special reference to a characteristic increase and prolongation of the hyperbilirubinemic response to nicotinic acid.

Authors:  V L Fromke; D Miller
Journal:  Medicine (Baltimore)       Date:  1972-11       Impact factor: 1.889

10.  [Recent advances in pathogenesis and diagnosis of constitutional hepatic dysfunction (Gilbert's syndrome) (author's transl)].

Authors:  W Röllinghoff; R Preisig
Journal:  Ther Umsch       Date:  1978-09
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  2 in total

1.  Orthotopic liver transplantation in liver-based metabolic disorders.

Authors:  A P Mowat
Journal:  Eur J Pediatr       Date:  1992       Impact factor: 3.183

Review 2.  Treatment of inherited metabolic disorders by liver transplantation.

Authors:  M Burdelski; B Rodeck; A Latta; K Latta; J Brodehl; B Ringe; R Pichlmayr
Journal:  J Inherit Metab Dis       Date:  1991       Impact factor: 4.982

  2 in total

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