Annik Plourde1, Kim L Lavoie1, Candace Raddatz2, Simon L Bacon3. 1. Montreal Behavioural Medicine Centre, CIUSSS-NIM, Hôpital du Sacré-Cœur de Montréal, Canada; Research Centre, CIUSSS-NIM, Hôpital du Sacré-Cœur de Montréal, Canada; Department of Psychology, Université du Québec à Montréal (UQAM), Canada. 2. Montreal Behavioural Medicine Centre, CIUSSS-NIM, Hôpital du Sacré-Cœur de Montréal, Canada; Research Centre, CIUSSS-NIM, Hôpital du Sacré-Cœur de Montréal, Canada; Department of Exercise Science, Concordia University, Montreal, Canada. 3. Montreal Behavioural Medicine Centre, CIUSSS-NIM, Hôpital du Sacré-Cœur de Montréal, Canada; Research Centre, CIUSSS-NIM, Hôpital du Sacré-Cœur de Montréal, Canada; Department of Exercise Science, Concordia University, Montreal, Canada. Electronic address: simon.bacon@concordia.ca.
Abstract
BACKGROUND: Psychological stress has long been suspected to have a deleterious effect on asthma, with acute psychological stress being associated with physiological responses in asthma patients. OBJECTIVES: The purpose of this systematic review was to provide a narrative synthesis of the impact of acute laboratory psychological stress on physiological responses among asthma patients. METHODS: An extensive search was conducted by two independent authors using Pubmed, PsycINFO, PsyArticles and the Cochrane Library electronic databases (up to September 2016). English and French articles which assessed physiological responses during or post-stress and compare them to baseline or pre-stress values were included. RESULTS: Thirty-two studies met the inclusion criteria. Studies indicated that exposure to active stressors (e.g., arithmetic tasks) was associated with an increase in sympathetic nervous system (SNS) responses, cortisol, and inflammatory responses, but had little effect on the caliber of the bronchi. Exposure to passive stressors (e.g., watching stressful movies or pictures) was also associated with an increase in SNS responses and with mild bronchoconstriction. However, a paucity of data for passive stressors limited conclusions on other measures. CONCLUSIONS: In patients with asthma, both active and passive stressors seem to be associated with an increased activation of the SNS. Passive stressors seem to have a more immediate, deleterious impact on the airways than active stressors, but the latter may be associated with delayed inflammatory driven an asthma exacerbation. Further studies are needed to understand the impact of acute stressors on the physiological mechanisms associated with asthma, particularly HPA and immune markers. Systematic review registration number: CRD42015026431.
BACKGROUND: Psychological stress has long been suspected to have a deleterious effect on asthma, with acute psychological stress being associated with physiological responses in asthmapatients. OBJECTIVES: The purpose of this systematic review was to provide a narrative synthesis of the impact of acute laboratory psychological stress on physiological responses among asthmapatients. METHODS: An extensive search was conducted by two independent authors using Pubmed, PsycINFO, PsyArticles and the Cochrane Library electronic databases (up to September 2016). English and French articles which assessed physiological responses during or post-stress and compare them to baseline or pre-stress values were included. RESULTS: Thirty-two studies met the inclusion criteria. Studies indicated that exposure to active stressors (e.g., arithmetic tasks) was associated with an increase in sympathetic nervous system (SNS) responses, cortisol, and inflammatory responses, but had little effect on the caliber of the bronchi. Exposure to passive stressors (e.g., watching stressful movies or pictures) was also associated with an increase in SNS responses and with mild bronchoconstriction. However, a paucity of data for passive stressors limited conclusions on other measures. CONCLUSIONS: In patients with asthma, both active and passive stressors seem to be associated with an increased activation of the SNS. Passive stressors seem to have a more immediate, deleterious impact on the airways than active stressors, but the latter may be associated with delayed inflammatory driven an asthma exacerbation. Further studies are needed to understand the impact of acute stressors on the physiological mechanisms associated with asthma, particularly HPA and immune markers. Systematic review registration number: CRD42015026431.
Authors: Rocío Lavigne-Cerván; Borja Costa-López; Rocío Juárez-Ruiz de Mier; Marta Real-Fernández; Marta Sánchez-Muñoz de León; Ignasi Navarro-Soria Journal: Front Psychol Date: 2021-02-16
Authors: Wen Yan Jiao; Lin Na Wang; Juan Liu; Shuan Feng Fang; Fu Yong Jiao; Massimo Pettoello-Mantovani; Eli Somekh Journal: J Pediatr Date: 2020-04-03 Impact factor: 4.406