| Literature DB >> 28501303 |
Wilhelm Kriz1, Kevin V Lemley2.
Abstract
Filtrate flow through the glomerular barrier produces shear stresses that tend to disconnect podocytes from the glomerular basement membrane. Forces are highest within the filtration slits. The slit diaphragm mechanically balances the lateral components of the shear stresses on opposing foot processes, preventing widening of the slit.Mesh:
Year: 2017 PMID: 28501303 DOI: 10.1016/j.kint.2017.02.032
Source DB: PubMed Journal: Kidney Int ISSN: 0085-2538 Impact factor: 10.612