Chin Cheng1, Chieh-Liang Huang1, Chia-Jui Tsai2, Po-Han Chou3, Chih-Chien Lin4, Chin-Kuo Chang5. 1. Department of Psychiatry, China Medical University Hospital, China Medical University, Taichung, Taiwan. 2. Department of Psychiatry, Taichung Veterans General Hospital, Taichung, Taiwan; Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taiwan. 3. Department of Psychiatry, Taichung Veterans General Hospital, Taichung, Taiwan. 4. Department of Psychiatry, Taichung Veterans General Hospital, Taichung, Taiwan. Electronic address: cclin@vghtc.gov.tw. 5. Department of Psychological Medicine, Institute of Psychiatry, Psychology, and Neuroscience, King's College, London, United Kingdom.
Abstract
BACKGROUND: Alcohol-related dementia (ARD) is a heterogeneous long-term cognitive problem that can develop in the course of alcoholism. Current understanding of ARD remains limited. METHODS: We conducted a systematic review to synthesize available data on the epidemiology of ARD, through searching the relevant studies in the PubMed, PsycINFO, and ALOIS. "Alcohol" and "dementia" were used as keywords. RESULTS: We included articles published between January 1, 1991 and February 29, 2016, where language was not limited. Of the 9 identified articles, the prevalence of ARD ranged from 1.19/1000 in multiday admission patients residing in the United Kingdom to 25.6% in elderly clinic alcoholics from the United States. The proportion of ARD in early-onset dementia taken from 3 studies was approximately 10%, whereas only 1.28% in late-onset dementia taken from 1 study. CONCLUSIONS: Considering the relatively high proportion of ARD in early-onset dementia and its potentially reversible course, future investigation into ARD is necessary.
BACKGROUND:Alcohol-related dementia (ARD) is a heterogeneous long-term cognitive problem that can develop in the course of alcoholism. Current understanding of ARD remains limited. METHODS: We conducted a systematic review to synthesize available data on the epidemiology of ARD, through searching the relevant studies in the PubMed, PsycINFO, and ALOIS. "Alcohol" and "dementia" were used as keywords. RESULTS: We included articles published between January 1, 1991 and February 29, 2016, where language was not limited. Of the 9 identified articles, the prevalence of ARD ranged from 1.19/1000 in multiday admission patients residing in the United Kingdom to 25.6% in elderly clinic alcoholics from the United States. The proportion of ARD in early-onset dementia taken from 3 studies was approximately 10%, whereas only 1.28% in late-onset dementia taken from 1 study. CONCLUSIONS: Considering the relatively high proportion of ARD in early-onset dementia and its potentially reversible course, future investigation into ARD is necessary.
Authors: Dimitrios E Kouzoukas; Jennifer A Schreiber; Nuzhath F Tajuddin; Simon Kaja; Edward J Neafsey; Hee-Yong Kim; Michael A Collins Journal: Neurochem Int Date: 2019-06-25 Impact factor: 3.921
Authors: Jürgen Rehm; Omer S M Hasan; Sandra E Black; Kevin D Shield; Michaël Schwarzinger Journal: Alzheimers Res Ther Date: 2019-01-05 Impact factor: 6.982