Literature DB >> 28500428

A novel classification method for aid decision of traditional Chinese patent medicines for stroke treatment.

Yufeng Zhao1,2, Bo Liu3, Liyun He4, Wenjing Bai4, Xueyun Yu4, Xinyu Cao4,5, Lin Luo4, Peijing Rong6, Yuxue Zhao6, Guozheng Li5,7, Baoyan Liu8,9.   

Abstract

Traditional Chinese patent medicines are widely used to treat stroke because it has good efficacy in the clinical environment. However, because of the lack of knowledge on traditional Chinese patent medicines, many Western physicians, who are accountable for the majority of clinical prescriptions for such medicine, are confused with the use of traditional Chinese patent medicines. Therefore, the aid-decision method is critical and necessary to help Western physicians rationally use traditional Chinese patent medicines. In this paper, Manifold Ranking is employed to develop the aid-decision model of traditional Chinese patent medicines for stroke treatment. First, 115 stroke patients from three hospitals are recruited in the cross-sectional survey. Simultaneously, traditional Chinese physicians determine the traditional Chinese patent medicines appropriate for each patient. Second, particular indicators are explored to characterize the population feature of traditional Chinese patent medicines for stroke treatment. Moreover, these particular indicators can be easily obtained byWestern physicians and are feasible for widespread clinical application in the future. Third, the aid-decision model of traditional Chinese patent medicines for stroke treatment is constructed based on Manifold Ranking. Experimental results reveal that traditional Chinese patent medicines can be differentiated. Moreover, the proposed model can obtain high accuracy of aid decision.

Entities:  

Keywords:  aid decision; data mining; manifold ranking; stroke; traditional Chinese patent medicines

Mesh:

Substances:

Year:  2017        PMID: 28500428     DOI: 10.1007/s11684-017-0511-1

Source DB:  PubMed          Journal:  Front Med        ISSN: 2095-0217            Impact factor:   4.592


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