Literature DB >> 28497454

Efficacy of core decompression for treatment of canine femoral head osteonecrosis induced by arterial ischaemia and venous congestion.

Yupeng Liu1, Dewei Zhao1, Weiming Wang1, Yao Zhang1, Benjie Wang1, Zhigang Li1.   

Abstract

METHODS: 40 healthy mixed-breed dogs were randomly divided into 2 groups, arterial ischaemia (AI) and venous congestion (VC), each containing 20 dogs. The dogs underwent a procedure where the deep femoral artery or deep femoral vein was ligated randomly on the left or right side to establish the femoral head osteonecrosis model. 13 dogs from each group, AI and VC, were randomly selected for subsequent study. 3 dogs were randomly chosen from each group to receive core decompression (CD) every 2 weeks for a total of 4 sessions.
RESULTS: The development of femoral head osteonecrosis was slightly slowed at each measurement time point after CD in the arterial ischaemia (AI) group, but no restoration was observed. The venous congestion (VC) group showed a gradually reduced mixed signal after CD and exhibited a trend towards restoration. The various VC subgroups had significantly improved symptoms compared to the AI subgroups.
CONCLUSIONS: CD displayed greater treatment efficacy for femoral head osteonecrosis caused by VC, but poor efficacy for femoral head osteonecrosis caused by AI.

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Year:  2017        PMID: 28497454     DOI: 10.5301/hipint.5000462

Source DB:  PubMed          Journal:  Hip Int        ISSN: 1120-7000            Impact factor:   2.135


  1 in total

1.  Variation and significance of serum leptin, blood lipid level, adiponectin, NO and TNF-α for patients with non-traumatic ischemic necrosis of the femoral head.

Authors:  Bing Xu; Qiong-Hua Hu; Bo Zhao; Zong-Ke Zhou
Journal:  Saudi J Biol Sci       Date:  2017-11-09       Impact factor: 4.219

  1 in total

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