| Literature DB >> 28497379 |
K Werdan1,2, S Baldus3,4, N Frey3,5, U Nixdorff3,6, K-H Kuck3,7, H Katus3,8.
Abstract
This article describes controversially discussed Choosing wisely recommendations presented by the German Cardiac Society: anticoagulation therapy in patients with atrial fibrillation and "only" moderate stroke risk, on the one hand, and goal-directed low-density lipoprotein (LDL) cholesterol-lowering, on the other. Presuming an adequate regime, patients with atrial fibrillation and only moderate risk of stroke (CHA2DS2-VASc Score of 1 in men and of 2 in women) also benefit from anticoagulation therapy, even in elderly patients. In patients with coronary heart disease, the German Cardiac Society recommends reducing LDL-cholesterol serum levels with a statin to values lower than 70 mg/dl (1.8 mmol/l) or at least reducing the basal level by 50%. With this recommendation, the German Cardiac Society unequivocally prioritizes the "goal-oriented statin therapy" above the "statin strategy of fixed dose". The reasons for this preference are discussed.Entities:
Keywords: Anticoagulants; Atrial fibrillation; Cholesterol, LDL; Coronary disease; Hydroxymethylglutaryl-CoA reductase inhibitors
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Year: 2017 PMID: 28497379 DOI: 10.1007/s00108-017-0239-7
Source DB: PubMed Journal: Internist (Berl) ISSN: 0020-9554 Impact factor: 0.743