Literature DB >> 28497350

Synovial cellular and molecular markers in rheumatoid arthritis.

M Asif Amin1, David A Fox2, Jeffrey H Ruth1.   

Abstract

The profound alterations in the structure, cellular composition, and function of synovial tissue in rheumatoid arthritis (RA) are the basis for the persistent inflammation and cumulative joint destruction that are hallmarks of this disease. In RA, the synovium develops characteristics of a tertiary lymphoid organ, with extensive infiltration of lymphocytes and myeloid cells. Concurrently, the fibroblast-like synoviocytes undergo massive hyperplasia and acquire a tissue-invasive phenotype. In this review, we summarize key components of these processes, focusing on recently-described roles of selected molecular markers of these cellular components of RA synovitis.

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Year:  2017        PMID： 28497350      PMCID： PMC5521018          DOI： 10.1007/s00281-017-0631-3

Source DB:  PubMed          Journal:  Semin Immunopathol        ISSN： 1863-2297            Impact factor:   9.623


  103 in total

1.  Synovial tissue macrophage as a source of the chemotactic cytokine IL-8.

Authors:  A E Koch; S L Kunkel; J C Burrows; H L Evanoff; G K Haines; R M Pope; R M Strieter
Journal:  J Immunol       Date:  1991-10-01       Impact factor: 5.422

2.  Evidence that rheumatoid arthritis synovial T cells are similar to cytokine-activated T cells: involvement of phosphatidylinositol 3-kinase and nuclear factor kappaB pathways in tumor necrosis factor alpha production in rheumatoid arthritis.

Authors:  Fionula M Brennan; Amanda L Hayes; Cathleen J Ciesielski; Patricia Green; Brian M J Foxwell; Marc Feldmann
Journal:  Arthritis Rheum       Date:  2002-01

3.  Immunolocalization of membrane-type 1 MMP in human rheumatoid synovium tissues.

Authors:  Si Qin; Fengming Wang; Meng Zhou; Wen'ge Ding; Lujun Chen; Yahua Lu
Journal:  Int J Clin Exp Pathol       Date:  2015-08-01

4.  Cell surface expression of mouse macrosialin and human CD68 and their role as macrophage receptors for oxidized low density lipoprotein.

Authors:  M P Ramprasad; V Terpstra; N Kondratenko; O Quehenberger; D Steinberg
Journal:  Proc Natl Acad Sci U S A       Date:  1996-12-10       Impact factor: 11.205

5.  Citrulline is an essential constituent of antigenic determinants recognized by rheumatoid arthritis-specific autoantibodies.

Authors:  G A Schellekens; B A de Jong; F H van den Hoogen; L B van de Putte; W J van Venrooij
Journal:  J Clin Invest       Date:  1998-01-01       Impact factor: 14.808

6.  Interleukin-8 as a macrophage-derived mediator of angiogenesis.

Authors:  A E Koch; P J Polverini; S L Kunkel; L A Harlow; L A DiPietro; V M Elner; S G Elner; R M Strieter
Journal:  Science       Date:  1992-12-11       Impact factor: 47.728

7.  Responsiveness of human T lymphocytes to bacterial superantigens presented by cultured rheumatoid arthritis synoviocytes.

Authors:  C Tsai; L A Diaz; N G Singer; L L Li; A H Kirsch; R Mitra; B J Nickoloff; L J Crofford; D A Fox
Journal:  Arthritis Rheum       Date:  1996-01

8.  Synovial fibroblasts spread rheumatoid arthritis to unaffected joints.

Authors:  Stephanie Lefèvre; Anette Knedla; Christoph Tennie; Andreas Kampmann; Christina Wunrau; Robert Dinser; Adelheid Korb; Eva-Maria Schnäker; Ingo H Tarner; Paul D Robbins; Christopher H Evans; Henning Stürz; Jürgen Steinmeyer; Steffen Gay; Jürgen Schölmerich; Thomas Pap; Ulf Müller-Ladner; Elena Neumann
Journal:  Nat Med       Date:  2009-11-08       Impact factor: 53.440

9.  Macrophage subpopulations in rheumatoid synovium: reduced CD163 expression in CD4+ T lymphocyte-rich microenvironments.

Authors:  J E Fonseca; J C W Edwards; S Blades; N J Goulding
Journal:  Arthritis Rheum       Date:  2002-05

10.  Blockade of collagen-induced arthritis post-onset by antibody to granulocyte-macrophage colony-stimulating factor (GM-CSF): requirement for GM-CSF in the effector phase of disease.

Authors:  A D Cook; E L Braine; I K Campbell; M J Rich; J A Hamilton
Journal:  Arthritis Res       Date:  2001-06-11
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  21 in total

1.  Rheumatoid arthritis: from basic findings and clinical manifestations to future therapies.

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Journal:  Semin Immunopathol       Date:  2017-06-21       Impact factor: 9.623

Review 2.  Inhibition of MMPs and ADAM/ADAMTS.

Authors:  Charles J Malemud
Journal:  Biochem Pharmacol       Date:  2019-02-28       Impact factor: 5.858

3.  Photobiomodulation effects in metalloproteinases expression in zymosan-induced arthritis.

Authors:  Lucia Mara Januário Dos Anjos; Anna Cecília Quirino-Teixeira; Eugenio Damasceno Hottz; Adenilson de Souza da Fonseca; Jacy Gameiro; Flávia de Paoli
Journal:  Lasers Med Sci       Date:  2022-09-26       Impact factor: 2.555

4.  miR-135a-5p mediated down-regulation of STAT6 inhibits proliferation and induces apoptosis of fibroblast-like synoviocytes in rheumatoid arthritis.

Authors:  Jiajia Liu; Jianhua Xue; Bo Xu; Junbo Yu; Yuxuan Zhang; Lili Qin; Aixian Zhang; Yang Yang
Journal:  Am J Transl Res       Date:  2022-05-15       Impact factor: 3.940

5.  Extracellular sulfatase-2 is overexpressed in rheumatoid arthritis and mediates the TNF-α-induced inflammatory activation of synovial fibroblasts.

Authors:  Ruby J Siegel; Anil K Singh; Paul M Panipinto; Farheen S Shaikh; Judy Vinh; Sang U Han; H Mark Kenney; Edward M Schwarz; Cynthia S Crowson; Sadik A Khuder; Basil S Khuder; David A Fox; Salahuddin Ahmed
Journal:  Cell Mol Immunol       Date:  2022-09-07       Impact factor: 22.096

6.  Comprehensive epigenetic landscape of rheumatoid arthritis fibroblast-like synoviocytes.

Authors:  Rizi Ai; Teresina Laragione; Deepa Hammaker; David L Boyle; Andre Wildberg; Keisuke Maeshima; Emanuele Palescandolo; Vinod Krishna; David Pocalyko; John W Whitaker; Yuchen Bai; Sunil Nagpal; Kurtis E Bachman; Richard I Ainsworth; Mengchi Wang; Bo Ding; Percio S Gulko; Wei Wang; Gary S Firestein
Journal:  Nat Commun       Date:  2018-05-15       Impact factor: 14.919

7.  A microfluidic chip-based co-culture of fibroblast-like synoviocytes with osteoblasts and osteoclasts to test bone erosion and drug evaluation.

Authors:  Hui-Peng Ma; Xue Deng; Deng-Yi Chen; Di Zhu; Jin-Ling Tong; Ting Zhao; Jin-Hui Ma; Yan-Qiu Liu
Journal:  R Soc Open Sci       Date:  2018-09-12       Impact factor: 2.963

8.  Sinomenine Inhibits the Progression of Rheumatoid Arthritis by Regulating the Secretion of Inflammatory Cytokines and Monocyte/Macrophage Subsets.

Authors:  Weiwei Liu; Yajie Zhang; Weina Zhu; Chunhua Ma; Jie Ruan; Hongyan Long; Yue Wang
Journal:  Front Immunol       Date:  2018-09-26       Impact factor: 7.561

9.  Cross-Tissue Transcriptomic Analysis Leveraging Machine Learning Approaches Identifies New Biomarkers for Rheumatoid Arthritis.

Authors:  Dmitry Rychkov; Jessica Neely; Tomiko Oskotsky; Steven Yu; Noah Perlmutter; Joanne Nititham; Alexander Carvidi; Melissa Krueger; Andrew Gross; Lindsey A Criswell; Judith F Ashouri; Marina Sirota
Journal:  Front Immunol       Date:  2021-06-08       Impact factor: 8.786

10.  Long Non-Coding RNA GAPLINC Promotes Tumor-Like Biologic Behaviors of Fibroblast-Like Synoviocytes as MicroRNA Sponging in Rheumatoid Arthritis Patients.

Authors:  Bi Yao Mo; Xing Hua Guo; Meng Ru Yang; Fang Liu; Xuan Bi; Yan Liu; Lin Kai Fang; Xi Qing Luo; Julie Wang; Joseph A Bellanti; Yun Feng Pan; Song Guo Zheng
Journal:  Front Immunol       Date:  2018-04-10       Impact factor: 7.561
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