Literature DB >> 28497242

[New Sepsis-3 definition : Do we have to treat sepsis before we can diagnose it from now on?]

T Schmoch1, M Bernhard2, F Uhle3, M Gründling4, T Brenner3, M A Weigand3.   

Abstract

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) have been available since the beginning of 2016. SEPSIS-3 completely replaces the old SIRS criteria in the definition of sepsis and defines sepsis from now on as "life-threatening organ dysfunction caused by a dysregulated host response to infection". However, it seems questionable whether in clinical practice the new definition is really superior to the old one. The most important question is the following: Is it helpful to have a definition that first recognizes a patient once organ dysfunction has occurred and the patient already needs intensive care?

Entities:  

Keywords:  Criticisms; Prognosis estimate; SOFA score; Sepsis-3; qSOFA

Mesh:

Year:  2017        PMID: 28497242     DOI: 10.1007/s00101-017-0316-2

Source DB:  PubMed          Journal:  Anaesthesist        ISSN: 0003-2417            Impact factor:   1.041


  36 in total

Review 1.  Sepsis: a roadmap for future research.

Authors:  Jonathan Cohen; Jean-Louis Vincent; Neill K J Adhikari; Flavia R Machado; Derek C Angus; Thierry Calandra; Katia Jaton; Stefano Giulieri; Julie Delaloye; Steven Opal; Kevin Tracey; Tom van der Poll; Eric Pelfrene
Journal:  Lancet Infect Dis       Date:  2015-04-19       Impact factor: 25.071

Review 2.  Opening the Debate on the New Sepsis Definition Change Is Not Necessarily Progress: Revision of the Sepsis Definition Should Be Based on New Scientific Insights.

Authors:  Irene Cortés-Puch; Christiane S Hartog
Journal:  Am J Respir Crit Care Med       Date:  2016-07-01       Impact factor: 21.405

3.  To SIRS With Love-An Open Letter.

Authors:  Charles L Sprung; Roland M H Schein; Robert A Balk
Journal:  Crit Care Med       Date:  2017-04       Impact factor: 7.598

4.  Clinical Mimics: An Emergency Medicine-Focused Review of Sepsis Mimics.

Authors:  Brit Long; Alex Koyfman
Journal:  J Emerg Med       Date:  2016-09-28       Impact factor: 1.484

Review 5.  Predictors of survival in sepsis: what is the best inflammatory marker to measure?

Authors:  Christoph Lichtenstern; Thorsten Brenner; Hubert J Bardenheuer; Markus A Weigand
Journal:  Curr Opin Infect Dis       Date:  2012-06       Impact factor: 4.915

Review 6.  2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference.

Authors:  Mitchell M Levy; Mitchell P Fink; John C Marshall; Edward Abraham; Derek Angus; Deborah Cook; Jonathan Cohen; Steven M Opal; Jean-Louis Vincent; Graham Ramsay
Journal:  Crit Care Med       Date:  2003-04       Impact factor: 7.598

7.  Definitions for Sepsis and Septic Shock.

Authors:  Shivinder Singh; Sanil Mohan; Ravi Singhal
Journal:  JAMA       Date:  2016-07-26       Impact factor: 56.272

8.  Systemic inflammatory response syndrome criteria in defining severe sepsis.

Authors:  Kirsi-Maija Kaukonen; Michael Bailey; David Pilcher; D Jamie Cooper; Rinaldo Bellomo
Journal:  N Engl J Med       Date:  2015-03-17       Impact factor: 91.245

9.  Use of the SOFA score to assess the incidence of organ dysfunction/failure in intensive care units: results of a multicenter, prospective study. Working group on "sepsis-related problems" of the European Society of Intensive Care Medicine.

Authors:  J L Vincent; A de Mendonça; F Cantraine; R Moreno; J Takala; P M Suter; C L Sprung; F Colardyn; S Blecher
Journal:  Crit Care Med       Date:  1998-11       Impact factor: 7.598

10.  Discovery and validation of cell cycle arrest biomarkers in human acute kidney injury.

Authors:  Kianoush Kashani; Ali Al-Khafaji; Thomas Ardiles; Antonio Artigas; Sean M Bagshaw; Max Bell; Azra Bihorac; Robert Birkhahn; Cynthia M Cely; Lakhmir S Chawla; Danielle L Davison; Thorsten Feldkamp; Lui G Forni; Michelle Ng Gong; Kyle J Gunnerson; Michael Haase; James Hackett; Patrick M Honore; Eric A J Hoste; Olivier Joannes-Boyau; Michael Joannidis; Patrick Kim; Jay L Koyner; Daniel T Laskowitz; Matthew E Lissauer; Gernot Marx; Peter A McCullough; Scott Mullaney; Marlies Ostermann; Thomas Rimmelé; Nathan I Shapiro; Andrew D Shaw; Jing Shi; Amy M Sprague; Jean-Louis Vincent; Christophe Vinsonneau; Ludwig Wagner; Michael G Walker; R Gentry Wilkerson; Kai Zacharowski; John A Kellum
Journal:  Crit Care       Date:  2013-02-06       Impact factor: 9.097

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  6 in total

Review 1.  [Evidence-based interdisciplinary treatment of abdominal sepsis].

Authors:  T Schmoch; M Al-Saeedi; A Hecker; D C Richter; T Brenner; T Hackert; M A Weigand
Journal:  Chirurg       Date:  2019-05       Impact factor: 0.955

2.  [Chameleon spondylodiscitis : Challenge for geriatricians].

Authors:  Werner Hofmann
Journal:  Nervenarzt       Date:  2018-06       Impact factor: 1.214

3.  [Sepsis detection in emergency medicine : Results of an interprofessional survey on sepsis detection in prehospital emergency medicine and emergency departments].

Authors:  C Metelmann; B Metelmann; C Scheer; M Gründling; B Henkel; K Hahnenkamp; P Brinkrolf
Journal:  Anaesthesist       Date:  2018-05-25       Impact factor: 1.041

Review 4.  Bacterial sepsis : Diagnostics and calculated antibiotic therapy.

Authors:  D C Richter; A Heininger; T Brenner; M Hochreiter; M Bernhard; J Briegel; S Dubler; B Grabein; A Hecker; W A Kruger; K Mayer; M W Pletz; D Storzinger; N Pinder; T Hoppe-Tichy; S Weiterer; S Zimmermann; A Brinkmann; M A Weigand; C Lichtenstern
Journal:  Anaesthesist       Date:  2019-02       Impact factor: 1.041

Review 5.  [Bacterial sepsis : Diagnostics and calculated antibiotic therapy].

Authors:  D C Richter; A Heininger; T Brenner; M Hochreiter; M Bernhard; J Briegel; S Dubler; B Grabein; A Hecker; W A Krüger; K Mayer; M W Pletz; D Störzinger; N Pinder; T Hoppe-Tichy; S Weiterer; S Zimmermann; A Brinkmann; M A Weigand; Christoph Lichtenstern
Journal:  Anaesthesist       Date:  2017-10       Impact factor: 1.041

6.  [Chameleon spondylodiscitis : Challenge for geriatricians].

Authors:  Werner Hofmann
Journal:  Z Gerontol Geriatr       Date:  2017-10-10       Impact factor: 1.281

  6 in total

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