Literature DB >> 28497182

The polo-like kinase 4 gene (PLK4) is overexpressed in pediatric medulloblastoma.

Simone Treiger Sredni1,2,3, Tadanori Tomita4,5.   

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Year:  2017        PMID: 28497182     DOI: 10.1007/s00381-017-3452-8

Source DB:  PubMed          Journal:  Childs Nerv Syst        ISSN: 0256-7040            Impact factor:   1.475


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  2 in total

1.  A functional screening of the kinome identifies the Polo-like kinase 4 as a potential therapeutic target for malignant rhabdoid tumors, and possibly, other embryonal tumors of the brain.

Authors:  Simone Treiger Sredni; Mario Suzuki; Jian-Ping Yang; Jacek Topczewski; Anders W Bailey; Tufan Gokirmak; Jeffrey N Gross; Alexandre de Andrade; Akihide Kondo; David R Piper; Tadanori Tomita
Journal:  Pediatr Blood Cancer       Date:  2017-04-11       Impact factor: 3.167

2.  PLK1-associated microRNAs are correlated with pediatric medulloblastoma prognosis.

Authors:  Julia Alejandra Pezuk; María Sol Brassesco; Ricardo Santos de Oliveira; Hélio Rubens Machado; Luciano Neder; Carlos Alberto Scrideli; Luiz Gonzaga Tone
Journal:  Childs Nerv Syst       Date:  2017-03-10       Impact factor: 1.475

  2 in total
  4 in total

1.  Polo-like kinase 4 inhibition produces polyploidy and apoptotic death of lung cancers.

Authors:  Masanori Kawakami; Lisa Maria Mustachio; Lin Zheng; Yulong Chen; Jaime Rodriguez-Canales; Barbara Mino; Jonathan M Kurie; Jason Roszik; Pamela Andrea Villalobos; Kelsie L Thu; Jennifer Silvester; David W Cescon; Ignacio I Wistuba; Tak W Mak; Xi Liu; Ethan Dmitrovsky
Journal:  Proc Natl Acad Sci U S A       Date:  2018-02-06       Impact factor: 11.205

2.  Centriole Overduplication is the Predominant Mechanism Leading to Centrosome Amplification in Melanoma.

Authors:  Ryan A Denu; Maria Shabbir; Minakshi Nihal; Chandra K Singh; B Jack Longley; Mark E Burkard; Nihal Ahmad
Journal:  Mol Cancer Res       Date:  2018-01-12       Impact factor: 5.852

Review 3.  STIL balancing primary microcephaly and cancer.

Authors:  Dhruti Patwardhan; Shyamala Mani; Sandrine Passemard; Pierre Gressens; Vincent El Ghouzzi
Journal:  Cell Death Dis       Date:  2018-01-19       Impact factor: 8.469

4.  Inhibition of polo-like kinase 4 (PLK4): a new therapeutic option for rhabdoid tumors and pediatric medulloblastoma.

Authors:  Simone Treiger Sredni; Anders W Bailey; Amreena Suri; Rintaro Hashizume; Xingyao He; Nundia Louis; Tufan Gokirmak; David R Piper; Daniel M Watterson; Tadanori Tomita
Journal:  Oncotarget       Date:  2017-11-24
  4 in total

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