Literature DB >> 28496771

Should Physicians Continue to Recommend Fish Oil for Patients with Atrial Fibrillation?

Victoria M Robinson1, Peter R Kowey2.   

Abstract

Many physicians recommend the use of fish oil or omega-3 polyunsaturated fatty acids (n-3 PUFA) in atrial fibrillation (AF) patients. N-3 PUFA have demonstrated anti-fibrillatory properties in several animal studies, however, data regarding their efficacy in preventing AF in humans have been mixed. This article critically reviews studies that have investigated the use of n-3 PUFA for the secondary prevention of paroxysmal and persistent AF and the primary prevention of post-operative AF. We conclude that n-3 PUFA should no longer be recommended for use in any of these AF subtypes until more data are available.

Entities:  

Year:  2012        PMID： 28496771      PMCID： PMC5153211          DOI： 10.4022/jafib.593

Source DB:  PubMed          Journal:  J Atr Fibrillation        ISSN： 1941-6911


  50 in total

1.  Polyunsaturated fatty acids for prevention of atrial fibrillation: a 'fishy' story.

Authors:  Irene Savelieva; A John Camm
Journal:  Europace       Date:  2011-02       Impact factor: 5.214

2.  Preoperative n-3 polyunsatured fatty acids are associated with a decrease in the incidence of early atrial fibrillation following cardiac surgery.

Authors:  Giovanni Mariscalco; Simona Sarzi Braga; Maciej Banach; Paolo Borsani; Vito Domenico Bruno; Martha Napoleone; Cristina Vitale; Gabriele Piffaretti; Roberto F E Pedretti; Andrea Sala
Journal:  Angiology       Date:  2010-06-07       Impact factor: 3.619

3.  Effect of dietary fish oil on atrial fibrillation after cardiac surgery.

Authors:  Aaron L Farquharson; Robert G Metcalf; Prashanthan Sanders; Robert Stuklis; James R M Edwards; Robert A Gibson; Leslie G Cleland; Thomas R Sullivan; Michael J James; Glenn D Young
Journal:  Am J Cardiol       Date:  2011-07-15       Impact factor: 2.778

4.  Antiarrhythmic and electrophysiological effects of long-chain omega-3 polyunsaturated fatty acids.

Authors:  Stefan Dhein; Bjela Michaelis; Friedrich-Wilhelm Mohr
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2005-04-15       Impact factor: 3.000

5.  Effects of n-3 polyunsaturated fatty acids on left ventricular function and functional capacity in patients with dilated cardiomyopathy.

Authors:  Savina Nodari; Marco Triggiani; Umberto Campia; Alessandra Manerba; Giuseppe Milesi; Bruno M Cesana; Mihai Gheorghiade; Livio Dei Cas
Journal:  J Am Coll Cardiol       Date:  2011-01-06       Impact factor: 24.094

6.  n-3 polyunsaturated fatty acids in the prevention of atrial fibrillation recurrences after electrical cardioversion: a prospective, randomized study.

Authors:  Savina Nodari; Marco Triggiani; Umberto Campia; Alessandra Manerba; Giuseppe Milesi; Bruno M Cesana; Mihai Gheorghiade; Livio Dei Cas
Journal:  Circulation       Date:  2011-08-15       Impact factor: 29.690

7.  Efficacy and safety of prescription omega-3-acid ethyl esters for the prevention of recurrent symptomatic atrial fibrillation: a prospective study.

Authors:  Craig M Pratt; James A Reiffel; Kenneth A Ellenbogen; Gerald V Naccarelli; Peter R Kowey
Journal:  Am Heart J       Date:  2009-08       Impact factor: 4.749

8.  Fish oil, but not flaxseed oil, decreases inflammation and prevents pressure overload-induced cardiac dysfunction.

Authors:  Monika K Duda; Karen M O'Shea; Anselm Tintinu; Wenhong Xu; Ramzi J Khairallah; Brian R Barrows; David J Chess; Agnes M Azimzadeh; William S Harris; Victor G Sharov; Hani N Sabbah; William C Stanley
Journal:  Cardiovasc Res       Date:  2008-11-17       Impact factor: 10.787

Review 9.  Impact of dietary fatty acids on cardiac arrhythmogenesis.

Authors:  Julie H Rennison; David R Van Wagoner
Journal:  Circ Arrhythm Electrophysiol       Date:  2009-08

10.  Inverse shift in serum polyunsaturated and monounsaturated fatty acids is associated with adverse dilatation of the heart.

Authors:  H Rupp; T P Rupp; P Alter; B Maisch
Journal:  Heart       Date:  2009-08-31       Impact factor: 5.994
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