Osmar Antonio Centurion1, Shojiro Isomoto2, Akihiko Shimizu3. 1. Division of Electrophysiology and Arrhythmias, Cardiovascular Institute, Sanatorio Migone-Battilana, Asuncion, Paraguay. Departamento de Cardiologia. Primera Catedra de Clinica Medica. Universidad Nacional de Asuncion. 2. Health Screening Center, Japanese Red Cross Nagasaki Atomic Bomb Hospital, Nagasaki. 3. Faculty of Health Scinces, Yamaguchi Gradeate School of Medicine.
Abstract
Introduction: Paroxysmal atrial fibrillation (PAF) is a common arrhythmia, and it is associated with various cardiac conditions. On the other hand, lone PAF has no identifiable underlying cause, and can occur any time for no apparent reason. The underlying causes may modify the electrophysiological properties of the atrium in different ways and extent. However this setting may be different in patients with lone PAF. We sought to investigate the atrial electrophysiological properties in lone PAF. Material and Methods: This study included 62 control subjects (Control group) and 58 patients with lone PAF (LAF group). The following atrial vulnerability parameters induced by programmed atrial stimulation were assessed and quantitatively measured: 1) the atrial effective refractory period (ERP), 2) the atrial conduction delay (CD) zone, and 3) the maximum CD. Results: The mean atrial ERP of the Control group was 215±29 ms, and that of LAF group was 208±28 ms, p<0.05. The mean atrial CD zone of the LAF group was (50±28 ms) significantly greater than that of controls (34±22 ms) (p<0.01). The mean maximum CD of the LAF group (62±29 ms) was also significantly greater than that of controls (43±20 ms) (p<0.01). Conclusions : There is a greater conduction delay of the atrium and shorter refractoriness in patients with lone PAF. Patients without underlying causes for the development of PAF exhibit abnormalities in the electrophysiological properties of the atrium.
Introduction: Paroxysmal atrial fibrillation (PAF) is a common arrhythmia, and it is associated with various cardiac conditions. On the other hand, lone PAF has no identifiable underlying cause, and can occur any time for no apparent reason. The underlying causes may modify the electrophysiological properties of the atrium in different ways and extent. However this setting may be different in patients with lone PAF. We sought to investigate the atrial electrophysiological properties in lone PAF. Material and Methods: This study included 62 control subjects (Control group) and 58 patients with lone PAF (LAF group). The following atrial vulnerability parameters induced by programmed atrial stimulation were assessed and quantitatively measured: 1) the atrial effective refractory period (ERP), 2) the atrial conduction delay (CD) zone, and 3) the maximum CD. Results: The mean atrial ERP of the Control group was 215±29 ms, and that of LAF group was 208±28 ms, p<0.05. The mean atrial CD zone of the LAF group was (50±28 ms) significantly greater than that of controls (34±22 ms) (p<0.01). The mean maximum CD of the LAF group (62±29 ms) was also significantly greater than that of controls (43±20 ms) (p<0.01). Conclusions : There is a greater conduction delay of the atrium and shorter refractoriness in patients with lone PAF. Patients without underlying causes for the development of PAF exhibit abnormalities in the electrophysiological properties of the atrium.
Authors: S Isomoto; M Fukatani; A Konoe; M Tanigawa; O A Centurion; S Seto; T Hashimoto; M Kadena; A Shimizu; K Hashiba Journal: Jpn Circ J Date: 1992-08
Authors: Osmar Antonio Centurión; Karina Elizabeth Scavenius; Laura B García; Luis Miño; Judith Torales; Orlando Sequeira Journal: J Atr Fibrillation Date: 2018-06-30