| Literature DB >> 28495024 |
Joan A Geoghegan1, Timothy J Foster1, Pietro Speziale2, Yves F Dufrêne3.
Abstract
Live-cell nanoscopy has contributed significantly to assessing the inhibition of adhesion of uropathogenic Escherichia coli and Staphylococcus aureus by glycoconjugates and monoclonal antibodies, respectively, and of S. aureus surface attachment and cell-cell association by a synthetic peptide. This new technology shows promise for the development of antiadhesion therapies against bacterial pathogens.Entities:
Keywords: Staphylococcus aureus; antiadhesion therapy; bacterial adhesion; biofilms; nanoscopy
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Year: 2017 PMID: 28495024 DOI: 10.1016/j.tim.2017.04.002
Source DB: PubMed Journal: Trends Microbiol ISSN: 0966-842X Impact factor: 17.079