Literature DB >> 28495024

Live-Cell Nanoscopy in Antiadhesion Therapy.

Joan A Geoghegan1, Timothy J Foster1, Pietro Speziale2, Yves F Dufrêne3.   

Abstract

Live-cell nanoscopy has contributed significantly to assessing the inhibition of adhesion of uropathogenic Escherichia coli and Staphylococcus aureus by glycoconjugates and monoclonal antibodies, respectively, and of S. aureus surface attachment and cell-cell association by a synthetic peptide. This new technology shows promise for the development of antiadhesion therapies against bacterial pathogens.
Copyright © 2017 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Staphylococcus aureus; antiadhesion therapy; bacterial adhesion; biofilms; nanoscopy

Mesh:

Substances:

Year:  2017        PMID: 28495024     DOI: 10.1016/j.tim.2017.04.002

Source DB:  PubMed          Journal:  Trends Microbiol        ISSN: 0966-842X            Impact factor:   17.079


  5 in total

1.  Biofilm formation - what we can learn from recent developments.

Authors:  T Bjarnsholt; K Buhlin; Y F Dufrêne; M Gomelsky; A Moroni; M Ramstedt; K P Rumbaugh; T Schulte; L Sun; B Åkerlund; U Römling
Journal:  J Intern Med       Date:  2018-07-09       Impact factor: 8.989

Review 2.  How Microbes Use Force To Control Adhesion.

Authors:  Albertus Viljoen; Johann Mignolet; Felipe Viela; Marion Mathelié-Guinlet; Yves F Dufrêne
Journal:  J Bacteriol       Date:  2020-05-27       Impact factor: 3.490

3.  Staphylococcus aureus clumping factor A is a force-sensitive molecular switch that activates bacterial adhesion.

Authors:  Philippe Herman-Bausier; Cristina Labate; Aisling M Towell; Sylvie Derclaye; Joan A Geoghegan; Yves F Dufrêne
Journal:  Proc Natl Acad Sci U S A       Date:  2018-05-07       Impact factor: 11.205

4.  Calcium stabilizes the strongest protein fold.

Authors:  Lukas F Milles; Eduard M Unterauer; Thomas Nicolaus; Hermann E Gaub
Journal:  Nat Commun       Date:  2018-11-12       Impact factor: 14.919

5.  Inorganic nanosheets facilitate humoral immunity against medical implant infections by modulating immune co-stimulatory pathways.

Authors:  Chuang Yang; Yao Luo; Hao Shen; Min Ge; Jin Tang; Qiaojie Wang; Han Lin; Jianlin Shi; Xianlong Zhang
Journal:  Nat Commun       Date:  2022-08-18       Impact factor: 17.694

  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.