Literature DB >> 28494231

HIV Latency Gets a New Histone Mark.

Bryan C Nikolai1, Qin Feng2.   

Abstract

Transcriptional latency of integrated HIV-1 provirus represents a major obstacle to curing HIV. In this issue of Cell Host & Microbe, Boehm et al. (2017) identify a new lysine methyltransferase that writes a repressive histone mark associated with HIV-1 latency. The results are important for strategies to pharmacologically reverse HIV-1 latency.
Copyright © 2017 Elsevier Inc. All rights reserved.

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Year:  2017        PMID： 28494231      PMCID： PMC6484844          DOI： 10.1016/j.chom.2017.04.012

Source DB:  PubMed          Journal:  Cell Host Microbe        ISSN： 1931-3128            Impact factor:   21.023


  10 in total

Review 1.  Progress Toward HIV Eradication: Case Reports, Current Efforts, and the Challenges Associated with Cure.

Authors:  Alyssa R Martin; Robert F Siliciano
Journal:  Annu Rev Med       Date:  2015-11-02       Impact factor: 13.739

2.  Suv39H1 and HP1gamma are responsible for chromatin-mediated HIV-1 transcriptional silencing and post-integration latency.

Authors:  Isaure du Chéné; Euguenia Basyuk; Yea-Lih Lin; Robinson Triboulet; Anna Knezevich; Christine Chable-Bessia; Clement Mettling; Vincent Baillat; Jacques Reynes; Pierre Corbeau; Edouard Bertrand; Alessandro Marcello; Stephane Emiliani; Rosemary Kiernan; Monsef Benkirane
Journal:  EMBO J       Date:  2007-01-24       Impact factor: 11.598

3.  Recruitment of chromatin-modifying enzymes by CTIP2 promotes HIV-1 transcriptional silencing.

Authors:  Céline Marban; Stella Suzanne; Franck Dequiedt; Stéphane de Walque; Laetitia Redel; Carine Van Lint; Dominique Aunis; Olivier Rohr
Journal:  EMBO J       Date:  2007-01-24       Impact factor: 11.598

4.  SMYD2-Mediated Histone Methylation Contributes to HIV-1 Latency.

Authors:  Daniela Boehm; Mark Jeng; Gregory Camus; Andrea Gramatica; Roland Schwarzer; Jeffrey R Johnson; Philip A Hull; Mauricio Montano; Naoki Sakane; Sara Pagans; Robert Godin; Steven G Deeks; Nevan J Krogan; Warner C Greene; Melanie Ott
Journal:  Cell Host Microbe       Date:  2017-05-10       Impact factor: 21.023

Review 5.  Dysregulation of glucose metabolism in HIV patients: epidemiology, mechanisms, and management.

Authors:  Absalon D Gutierrez; Ashok Balasubramanyam
Journal:  Endocrine       Date:  2011-12-02       Impact factor: 3.633

6.  The Iws1:Spt6:CTD complex controls cotranscriptional mRNA biosynthesis and HYPB/Setd2-mediated histone H3K36 methylation.

Authors:  Sunnie M Yoh; Joseph S Lucas; Katherine A Jones
Journal:  Genes Dev       Date:  2008-12-15       Impact factor: 11.361

Review 7.  Latency reversal and viral clearance to cure HIV-1.

Authors:  David M Margolis; J Victor Garcia; Daria J Hazuda; Barton F Haynes
Journal:  Science       Date:  2016-07-22       Impact factor: 47.728

8.  Reactivation of latent HIV-1 by inhibition of BRD4.

Authors:  Jian Zhu; Gaurav D Gaiha; Sinu P John; Thomas Pertel; Christopher R Chin; Geng Gao; Hongjing Qu; Bruce D Walker; Stephen J Elledge; Abraham L Brass
Journal:  Cell Rep       Date:  2012-10-04       Impact factor: 9.423

9.  LSD1 cooperates with CTIP2 to promote HIV-1 transcriptional silencing.

Authors:  Valentin Le Douce; Laurence Colin; Laetitia Redel; Thomas Cherrier; Georges Herbein; Dominique Aunis; Olivier Rohr; Carine Van Lint; Christian Schwartz
Journal:  Nucleic Acids Res       Date:  2011-11-08       Impact factor: 16.971

10.  Multiple Histone Lysine Methyltransferases Are Required for the Establishment and Maintenance of HIV-1 Latency.

Authors:  Kien Nguyen; Biswajit Das; Curtis Dobrowolski; Jonathan Karn
Journal:  mBio       Date:  2017-02-28       Impact factor: 7.867
  10 in total
  3 in total

1.  Circular RNA Profiles in Viremia and ART Suppression Predict Competing circRNA-miRNA-mRNA Networks Exclusive to HIV-1 Viremic Patients.

Authors:  Dora Zucko; Abdullgadir Hayir; Kelsey Grinde; Kathleen Boris-Lawrie
Journal:  Viruses       Date:  2022-03-25       Impact factor: 5.818

Review 2.  Epigenetic regulation of HIV-1 latency: focus on polycomb group (PcG) proteins.

Authors:  Sheraz Khan; Mazhar Iqbal; Muhammad Tariq; Shahid M Baig; Wasim Abbas
Journal:  Clin Epigenetics       Date:  2018-02-05       Impact factor: 6.551

3.  Novel pathways of HIV latency reactivation revealed by integrated analysis of transcriptome and target profile of bryostatin.

Authors:  Bing-Xiang Li; Han Zhang; Yubin Liu; Ya Li; Jun-Juan Zheng; Wen-Xing Li; Kai Feng; Ming Sun; Shao-Xing Dai
Journal:  Sci Rep       Date:  2020-02-26       Impact factor: 4.379
  3 in total

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