Michael Kostrzewa1, Kerim Kara2, Lothar Pilz3, Hannelore Mueller-Muertz4, Nils Rathmann5, Stefan O Schoenberg5, Steffen J Diehl5. 1. Institute of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, Medical Faculty Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany. michael.kostrzewa@umm.de. 2. Fraunhofer Project Group for Automation in Medicine and Biotechnology, Medical Faculty Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany. 3. Department of Surgery/Thoracic Oncology, University Medical Center Mannheim, Medical Faculty Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany. 4. Department of Internal Medicine I, Cardiology/AngiologyUniversity Medical Center Mannheim, Medical Faculty Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany. 5. Institute of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, Medical Faculty Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.
Abstract
PURPOSE: To evaluate the hemodynamic effect of percutaneous transluminal intervention (PTI) on stenosis of the superficial femoral (SFA) and popliteal arteries (PA) using time-density curves (TDCs) derived from digital subtraction angiography (DSA) series in correlation with ultrasound peak systolic velocity ratio (PSVR) and ankle brachial index (ABI). MATERIALS AND METHODS: DSA series of SFA or PA of patients with symptomatic peripheral arterial occlusive disease was obtained with a flat-panel angiography system with intention-to-treat. In DSA series acquired before and after PTI, TDCs were analyzed proximal and distal of each stenosis using parametric color coding (PCC). For correlation, ABI and PSVR measurements pre- and post-PTI were recorded for all patients. RESULTS: In total, 25 stenoses of the SFA or PA were treated by PTI in 22 patients (17 male, 5 female, mean age 68 years). After treatment, peak-to-peak (PTP) times between TDCs proximal and distal to the treated vessel segment decreased statistically significantly (p = 0.01) on average from PTP = 1.9 ± 1.7 s to mean PTP = 1 ± 1 s. ABI and PSVR also changed statistically significantly after treatment (pretreatment ABI = 0.7 ± 0.2, PSVR = 4.2 ± 1.9; post-ABI = 0.9 ± 0.2, PSVR = 1.3 ± 0.4, both p < 0.05). Correlation parameters did not show a strong correlation between change in TDC and clinical parameters ABI and PSVR. CONCLUSION: Using PCC for analyzing contrast medium dynamics in DSA series is clinically useful for evaluating stenoses of the SFA and PA and for immediate treatment control after PTA. LEVEL OF EVIDENCE: Case series, IV.
PURPOSE: To evaluate the hemodynamic effect of percutaneous transluminal intervention (PTI) on stenosis of the superficial femoral (SFA) and popliteal arteries (PA) using time-density curves (TDCs) derived from digital subtraction angiography (DSA) series in correlation with ultrasound peak systolic velocity ratio (PSVR) and ankle brachial index (ABI). MATERIALS AND METHODS: DSA series of SFA or PA of patients with symptomatic peripheral arterial occlusive disease was obtained with a flat-panel angiography system with intention-to-treat. In DSA series acquired before and after PTI, TDCs were analyzed proximal and distal of each stenosis using parametric color coding (PCC). For correlation, ABI and PSVR measurements pre- and post-PTI were recorded for all patients. RESULTS: In total, 25 stenoses of the SFA or PA were treated by PTI in 22 patients (17 male, 5 female, mean age 68 years). After treatment, peak-to-peak (PTP) times between TDCs proximal and distal to the treated vessel segment decreased statistically significantly (p = 0.01) on average from PTP = 1.9 ± 1.7 s to mean PTP = 1 ± 1 s. ABI and PSVR also changed statistically significantly after treatment (pretreatment ABI = 0.7 ± 0.2, PSVR = 4.2 ± 1.9; post-ABI = 0.9 ± 0.2, PSVR = 1.3 ± 0.4, both p < 0.05). Correlation parameters did not show a strong correlation between change in TDC and clinical parameters ABI and PSVR. CONCLUSION: Using PCC for analyzing contrast medium dynamics in DSA series is clinically useful for evaluating stenoses of the SFA and PA and for immediate treatment control after PTA. LEVEL OF EVIDENCE: Case series, IV.
Entities:
Keywords:
Ankle brachial index; Digital subtraction angiography; Parametric color coding; Peak systolic velocity ratio; Peripheral arterial occlusive disease
Authors: Anne Marie Augustin; Irina Thein; Nicole Rickert; Thorsten Klink; Thorsten Alexander Bley; Ralph Kickuth Journal: BMC Med Imaging Date: 2020-06-18 Impact factor: 1.930
Authors: Patrick Ghibes; Sasan Partovi; Gerd Grözinger; Petros Martirosian; Fritz Schick; Konstantin Nikolaou; Dominik Ketelsen; Roland Syha; Ulrich Grosse Journal: Biomed Res Int Date: 2018-07-24 Impact factor: 3.411
Authors: Patrick Ghibes; Gerald Hefferman; Konstantin Nikolaou; Roland Syha; Christoph Artzner; Ulrich Grosse; Rüdiger Hoffmann; Gerd Grözinger Journal: Biomed Res Int Date: 2020-01-16 Impact factor: 3.411
Authors: Anne Marie Augustin; Stefan Welsch; Thorsten Alexander Bley; Kai Lopau; Ralph Kickuth Journal: BMC Med Imaging Date: 2021-02-10 Impact factor: 1.930