Literature DB >> 28486099

A TIAM Double Hit to Oppose YAP/TAZ.

Luca Azzolin1, Stefano Piccolo2.   

Abstract

In this issue of Cancer Cell, Diamantopoulou et al. uncover dual mechanisms of inhibiting YAP/TAZ by TIAM1 that oppose invasiveness of colorectal cancer cells: TIAM1 interacts with TAZ in the cytoplasm to promote TAZ degradation by the destruction complex, whereas it antagonizes binding of TAZ/YAP to TEAD in the nucleus.
Copyright © 2017 Elsevier Inc. All rights reserved.

Entities:  

Mesh：

Substances：

Year:  2017        PMID： 28486099      PMCID： PMC6203307          DOI： 10.1016/j.ccell.2017.04.009

Source DB:  PubMed          Journal:  Cancer Cell        ISSN： 1535-6108            Impact factor:   31.743


  9 in total

1.  The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells.

Authors:  Michelangelo Cordenonsi; Francesca Zanconato; Luca Azzolin; Mattia Forcato; Antonio Rosato; Chiara Frasson; Masafumi Inui; Marco Montagner; Anna R Parenti; Alessandro Poletti; Maria Grazia Daidone; Sirio Dupont; Giuseppe Basso; Silvio Bicciato; Stefano Piccolo
Journal:  Cell       Date:  2011-11-11       Impact factor: 41.582

2.  Repression of Intestinal Stem Cell Function and Tumorigenesis through Direct Phosphorylation of β-Catenin and Yap by PKCζ.

Authors:  Victoria Llado; Yuki Nakanishi; Angeles Duran; Miguel Reina-Campos; Phillip M Shelton; Juan F Linares; Tomoko Yajima; Alex Campos; Pedro Aza-Blanc; Michael Leitges; Maria T Diaz-Meco; Jorge Moscat
Journal:  Cell Rep       Date:  2015-02-05       Impact factor: 9.423

3.  Role of TAZ as mediator of Wnt signaling.

Authors:  Luca Azzolin; Francesca Zanconato; Silvia Bresolin; Mattia Forcato; Giuseppe Basso; Silvio Bicciato; Michelangelo Cordenonsi; Stefano Piccolo
Journal:  Cell       Date:  2012-12-13       Impact factor: 41.582

4.  YAP/TAZ incorporation in the β-catenin destruction complex orchestrates the Wnt response.

Authors:  Luca Azzolin; Tito Panciera; Sandra Soligo; Elena Enzo; Silvio Bicciato; Sirio Dupont; Silvia Bresolin; Chiara Frasson; Giuseppe Basso; Vincenza Guzzardo; Ambrogio Fassina; Michelangelo Cordenonsi; Stefano Piccolo
Journal:  Cell       Date:  2014-06-26       Impact factor: 41.582

5.  WIP Drives Tumor Progression through YAP/TAZ-Dependent Autonomous Cell Growth.

Authors:  Ricardo Gargini; Maribel Escoll; Esther García; Ramón García-Escudero; Francisco Wandosell; Inés María Antón
Journal:  Cell Rep       Date:  2016-11-15       Impact factor: 9.423

6.  Tiam1-deficiency impairs mammary tumor formation in MMTV-c-neu but not in MMTV-c-myc mice.

Authors:  K Strumane; T Rygiel; M van der Valk; J G Collard
Journal:  J Cancer Res Clin Oncol       Date:  2008-07-01       Impact factor: 4.553

7.  SETD7 Controls Intestinal Regeneration and Tumorigenesis by Regulating Wnt/β-Catenin and Hippo/YAP Signaling.

Authors:  Menno J Oudhoff; Mitchell J S Braam; Spencer A Freeman; Denise Wong; David G Rattray; Jia Wang; Frann Antignano; Kimberly Snyder; Ido Refaeli; Michael R Hughes; Kelly M McNagny; Michael R Gold; Cheryl H Arrowsmith; Toshiro Sato; Fabio M V Rossi; John H Tatlock; Dafydd R Owen; Peter J Brown; Colby Zaph
Journal:  Dev Cell       Date:  2016-04-04       Impact factor: 12.270

8.  β-Catenin destruction complex-independent regulation of Hippo-YAP signaling by APC in intestinal tumorigenesis.

Authors:  Jing Cai; Anirban Maitra; Robert A Anders; Makoto M Taketo; Duojia Pan
Journal:  Genes Dev       Date:  2015-07-20       Impact factor: 11.361

Review 9.  Deregulation of Rho GTPases in cancer.

Authors:  Andrew P Porter; Alexandra Papaioannou; Angeliki Malliri
Journal:  Small GTPases       Date:  2016-04-22
  9 in total
  2 in total

Review 1.  Dual roles of yes-associated protein (YAP) in colorectal cancer.

Authors:  Chunlin Ou; Zhenqiang Sun; Shen Li; Guiyuan Li; Xiayu Li; Jian Ma
Journal:  Oncotarget       Date:  2017-08-11

2.  RASAL2 mediated the enhancement of YAP1/TIAM1 signaling promotes malignant phenotypes of pancreatic ductal adenocarcinoma.

Authors:  Yangyang Yue; Kaijie Wu; Weikun Qian; Zeen Zhu; Simei Zhang; Wunai Zhang; Weifan Zhang; Shuai Wu; Li Li; Zheng Wu; Qingyong Ma; Keping Xie; Zheng Wang
Journal:  Int J Biol Sci       Date:  2022-06-27       Impact factor: 10.750
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.