Literature DB >> 28485663

Can 8 months of daily tDCS application slow the cognitive decline in Alzheimer's disease? A case study.

Martin Bystad1,2, Ingrid Daae Rasmussen1, Ole Grønli2, Per M Aslaksen1,3.   

Abstract

This case study presents a patient with early-onset Alzheimer`s disease, who applied transcranial direct current stimulation (tDCS) daily for 8 consecutive months. This was a much higher frequency than previous tDCS studies. Neuropsychological assessments were conducted before the first tDCS session, after 5 months and after 8 months. After 8 months, the patient's immediate recall improved with 39%, whereas delayed recall improved 23%. Overall, the results revealed that patient's cognitive functions were stabilized. There may be slight possibility that tDCS could slow the cognitive decline in Alzheimer`s disease. This should be investigated in clinical trials.

Entities:  

Keywords:  Alzheimer’s disease; neuromodulation; tDCS; transcranial direct current stimulation

Mesh：

Year:  2017        PMID： 28485663     DOI： 10.1080/13554794.2017.1325911

Source DB:  PubMed          Journal:  Neurocase        ISSN： 1355-4794            Impact factor:   0.881


  11 in total

Review 1.  A Scoping Review of Neuromodulation Techniques in Neurodegenerative Diseases: A Useful Tool for Clinical Practice?

Authors:  Fabio Marson; Stefano Lasaponara; Marco Cavallo
Journal:  Medicina (Kaunas)       Date:  2021-02-27       Impact factor: 2.430

2.  Effects of 6-month at-home transcranial direct current stimulation on cognition and cerebral glucose metabolism in Alzheimer's disease.

Authors:  Jooyeon Jamie Im; Hyeonseok Jeong; Marom Bikson; Adam J Woods; Gozde Unal; Jin Kyoung Oh; Seunghee Na; Jong-Sik Park; Helena Knotkova; In-Uk Song; Yong-An Chung
Journal:  Brain Stimul       Date:  2019-06-04       Impact factor: 8.955

Review 3.  Past, Present, and Future of Non-invasive Brain Stimulation Approaches to Treat Cognitive Impairment in Neurodegenerative Diseases: Time for a Comprehensive Critical Review.

Authors:  Clara Sanches; Chloé Stengel; Juliette Godard; Justine Mertz; Marc Teichmann; Raffaella Migliaccio; Antoni Valero-Cabré
Journal:  Front Aging Neurosci       Date:  2021-01-20       Impact factor: 5.750

Review 4.  Therapeutic noninvasive brain stimulation in Alzheimer's disease and related dementias.

Authors:  Stephanie S Buss; Peter J Fried; Alvaro Pascual-Leone
Journal:  Curr Opin Neurol       Date:  2019-04       Impact factor: 5.710

5.  Guidelines for TMS/tES clinical services and research through the COVID-19 pandemic.

Authors:  Marom Bikson; Colleen A Hanlon; Adam J Woods; Bernadette T Gillick; Leigh Charvet; Claus Lamm; Graziella Madeo; Adrienn Holczer; Jorge Almeida; Andrea Antal; Mohammad Reza Ay; Chris Baeken; Daniel M Blumberger; Salvatore Campanella; Joan A Camprodon; Lasse Christiansen; Colleen Loo; Jennifer T Crinion; Paul Fitzgerald; Luigi Gallimberti; Peyman Ghobadi-Azbari; Iman Ghodratitoostani; Roland H Grabner; Gesa Hartwigsen; Akimasa Hirata; Adam Kirton; Helena Knotkova; Evgeny Krupitsky; Paola Marangolo; Ester M Nakamura-Palacios; Weronika Potok; Samir K Praharaj; Christian C Ruff; Gottfried Schlaug; Hartwig R Siebner; Charlotte J Stagg; Axel Thielscher; Nicole Wenderoth; Ti-Fei Yuan; Xiaochu Zhang; Hamed Ekhtiari
Journal:  Brain Stimul       Date:  2020-05-12       Impact factor: 8.955

6.  Effects of short- and long-term neurostimulation (tDCS) on Alzheimer's disease patients: two randomized studies.

Authors:  Antonio Gangemi; Barbara Colombo; Rosa Angela Fabio
Journal:  Aging Clin Exp Res       Date:  2020-04-16       Impact factor: 3.636

7.  Rapid, Dose-Dependent Enhancement of Cerebral Blood Flow by transcranial AC Stimulation in Mouse.

Authors:  Dennis A Turner; Simone Degan; Francesca Galeffi; Stephen Schmidt; Angel V Peterchev
Journal:  Brain Stimul       Date:  2020-11-18       Impact factor: 8.955

8.  Can Transcranial Direct-Current Stimulation Alone or Combined With Cognitive Training Be Used as a Clinical Intervention to Improve Cognitive Functioning in Persons With Mild Cognitive Impairment and Dementia? A Systematic Review and Meta-Analysis.

Authors:  Pablo Cruz Gonzalez; Kenneth N K Fong; Raymond C K Chung; Kin-Hung Ting; Lawla L F Law; Ted Brown
Journal:  Front Hum Neurosci       Date:  2018-10-16       Impact factor: 3.169

9.  Neurostimulation Combined With Cognitive Intervention in Alzheimer's Disease (NeuroAD): Study Protocol of Double-Blind, Randomized, Factorial Clinical Trial.

Authors:  Suellen Marinho Andrade; Eliane Araújo de Oliveira; Nelson Torro Alves; Ana Cristina Gomes Dos Santos; Camila Teresa Ponce Leon de Mendonça; Danielle Dorand Amorim Sampaio; Edyllaine Elidy Querino Cavalcante da Silva; Égina Karoline Gonçalves da Fonsêca; Evelyn Thais de Almeida Rodrigues; Gabriela Nayara Siqueira de Lima; Jamerson Carvalho; Jessyca Alves Silvestre da Silva; Manuella Toledo; Marine Raquel Diniz da Rosa; Marcia Queiroz de Carvalho Gomes; Melquisedek Monteiro de Oliveira; Moema Teixeira Maia Lemos; Nágylla Gomes Lima; Penha Inácio; Petra Maria da Cruz Ribeiro E Rodrigues; Rayssa Gabriela Dantas Ferreira; Renata Cavalcante; Renata Emanuela Lyra de Brito Aranha; Regina Neves; Rodrigo Marmo da Costa E Souza; Thainá Magalhães Portugal; Wanessa Kallyne Nascimento Martins; Vivian Pontes; Thiago Monteiro de Paiva Fernandes; Israel Contador; Bernardino Fernández-Calvo
Journal:  Front Aging Neurosci       Date:  2018-11-02       Impact factor: 5.750

10.  Feasibility of remotely supervised transcranial direct current stimulation and cognitive remediation: A systematic review.

Authors:  Nicole Gough; Lea Brkan; Ponnusamy Subramaniam; Lina Chiuccariello; Alessandra De Petrillo; Benoit H Mulsant; Christopher R Bowie; Tarek K Rajji
Journal:  PLoS One       Date:  2020-02-24       Impact factor: 3.240
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