| Literature DB >> 28485421 |
Huijun Yuan1, Lili Zhang, Zhantao Liu, Yang Liu, Jian Wang, Wenjun Li.
Abstract
A NHC-catalyzed 1,3-dipolar cycloaddition reaction of allyl ketones with azides has been developed. This strategy could generate 1,4,5-trisubstituted 1,2,3-triazoles in high yields and regioselectivities in the presence of a 20 mol% N-heterocyclic carbene catalyst. A broad substrate scope of this process is also presented.Entities:
Year: 2017 PMID： 28485421 DOI： 10.1039/c7ob00906b
Source DB: PubMed Journal: Org Biomol Chem ISSN： 1477-0520 Impact factor: 3.876