Dana Elena Giza1, Kostas Marmagkiolis2, Elie Mouhayar1, Jean-Bernard Durand1, Cezar Iliescu3. 1. Department of Cardiology, University of Texas MD Anderson Cancer Center, 1400 Pressler Street, Houston, TX, 77030, USA. 2. Department of Cardiology, University of Missouri, Columbia, 1500 N Oakland Ave, Bolivar, MO, 65613, USA. 3. Department of Cardiology, University of Texas MD Anderson Cancer Center, 1400 Pressler Street, Houston, TX, 77030, USA. ciliescu@mdanderson.org.
Abstract
PURPOSE OF REVIEW: Coronary artery disease in patients with active cancer presents particular challenges for clinicians, as optimum management is required in order to treat the underlying malignancy and to reduce morbidity and mortality associated with cardiovascular diseases. Special considerations must be made in respect to either primary or secondary thrombocytopenia, the presence of coagulopathies and the propensity of bleeding, vascular access complications, and increased risk of stent thrombosis. RECENT FINDINGS: In presence of acute coronary symptoms, the cardio-oncology team has to make a complex decision between conservative medical management or early angiography (within 24 h) and revascularization. There is a lack of reliable data on the outcomes of patients with active cancer who undergo invasive procedures for the diagnostic and treatment of coronary artery disease. Cardiac catheterization recommendations in cancer patients are being currently elaborated by cardio-oncologists in order to improve the overall survival in cancer patients with coronary artery disease.
PURPOSE OF REVIEW: Coronary artery disease in patients with active cancer presents particular challenges for clinicians, as optimum management is required in order to treat the underlying malignancy and to reduce morbidity and mortality associated with cardiovascular diseases. Special considerations must be made in respect to either primary or secondary thrombocytopenia, the presence of coagulopathies and the propensity of bleeding, vascular access complications, and increased risk of stent thrombosis. RECENT FINDINGS: In presence of acute coronary symptoms, the cardio-oncology team has to make a complex decision between conservative medical management or early angiography (within 24 h) and revascularization. There is a lack of reliable data on the outcomes of patients with active cancer who undergo invasive procedures for the diagnostic and treatment of coronary artery disease. Cardiac catheterization recommendations in cancerpatients are being currently elaborated by cardio-oncologists in order to improve the overall survival in cancerpatients with coronary artery disease.
Authors: Matthijs A Velders; Helèn Boden; Sjoerd H Hofma; Susanne Osanto; Bas L van der Hoeven; Anton A C M Heestermans; Suzanne C Cannegieter; J Wouter Jukema; Victor A W M Umans; Martin J Schalij; Adrianus J van Boven Journal: Am J Cardiol Date: 2013-09-21 Impact factor: 2.778
Authors: Nicole Thomason; Dominique J Monlezun; Awad Javaid; Alexandru Filipescu; Efstratios Koutroumpakis; Fisayomi Shobayo; Peter Kim; Juan Lopez-Mattei; Mehmet Cilingiroglu; Gloria Iliescu; Kostas Marmagkiolis; Pedro T Ramirez; Cezar Iliescu Journal: Front Cardiovasc Med Date: 2022-02-14