Literature DB >> 28483955

In Vitro Activity of a Novel Glucan Synthase Inhibitor, SCY-078, against Clinical Isolates of Candida auris.

Elizabeth L Berkow1, David Angulo2, Shawn R Lockhart3.   

Abstract

Entities:  

Keywords:  Candida auris; SCY-078

Mesh：

Substances：

Year:  2017        PMID： 28483955      PMCID： PMC5487607          DOI： 10.1128/AAC.00435-17

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


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  7 in total

1.  Enfumafungin derivative MK-3118 shows increased in vitro potency against clinical echinocandin-resistant Candida Species and Aspergillus species isolates.

Authors:  Cristina Jiménez-Ortigosa; Padmaja Paderu; Mary R Motyl; David S Perlin
Journal:  Antimicrob Agents Chemother       Date:  2013-12-09       Impact factor: 5.191

Review 2.  Multidrug-resistant Candida auris: 'new kid on the block' in hospital-associated infections?

Authors:  A Chowdhary; A Voss; J F Meis
Journal:  J Hosp Infect       Date:  2016-08-15       Impact factor: 3.926

3.  Simultaneous Emergence of Multidrug-Resistant Candida auris on 3 Continents Confirmed by Whole-Genome Sequencing and Epidemiological Analyses.

Authors:  Shawn R Lockhart; Kizee A Etienne; Snigdha Vallabhaneni; Joveria Farooqi; Anuradha Chowdhary; Nelesh P Govender; Arnaldo Lopes Colombo; Belinda Calvo; Christina A Cuomo; Christopher A Desjardins; Elizabeth L Berkow; Mariana Castanheira; Rindidzani E Magobo; Kauser Jabeen; Rana J Asghar; Jacques F Meis; Brendan Jackson; Tom Chiller; Anastasia P Litvintseva
Journal:  Clin Infect Dis       Date:  2016-10-20       Impact factor: 9.079

4.  Investigation of the First Seven Reported Cases of Candida auris, a Globally Emerging Invasive, Multidrug-Resistant Fungus - United States, May 2013-August 2016.

Authors:  Snigdha Vallabhaneni; Alex Kallen; Sharon Tsay; Nancy Chow; Rory Welsh; Janna Kerins; Sarah K Kemble; Massimo Pacilli; Stephanie R Black; Emily Landon; Jessica Ridgway; Tara N Palmore; Adrian Zelzany; Eleanor H Adams; Monica Quinn; Sudha Chaturvedi; Jane Greenko; Rafael Fernandez; Karen Southwick; E Yoko Furuya; David P Calfee; Camille Hamula; Gopi Patel; Patricia Barrett; Patricia Lafaro; Elizabeth L Berkow; Heather Moulton-Meissner; Judith Noble-Wang; Ryan P Fagan; Brendan R Jackson; Shawn R Lockhart; Anastasia P Litvintseva; Tom M Chiller
Journal:  MMWR Morb Mortal Wkly Rep       Date:  2016-11-11       Impact factor: 17.586

5.  Pharmacodynamic target evaluation of a novel oral glucan synthase inhibitor, SCY-078 (MK-3118), using an in vivo murine invasive candidiasis model.

Authors:  Alexander J Lepak; Karen Marchillo; David R Andes
Journal:  Antimicrob Agents Chemother       Date:  2014-12-15       Impact factor: 5.191

6.  Activity of MK-3118, a new oral glucan synthase inhibitor, tested against Candida spp. by two international methods (CLSI and EUCAST).

Authors:  Michael A Pfaller; Shawn A Messer; Mary R Motyl; Ronald N Jones; Mariana Castanheira
Journal:  J Antimicrob Chemother       Date:  2012-11-28       Impact factor: 5.790

7.  The Emerging Pathogen Candida auris: Growth Phenotype, Virulence Factors, Activity of Antifungals, and Effect of SCY-078, a Novel Glucan Synthesis Inhibitor, on Growth Morphology and Biofilm Formation.

Authors:  Emily Larkin; Christopher Hager; Jyotsna Chandra; Pranab K Mukherjee; Mauricio Retuerto; Iman Salem; Lisa Long; Nancy Isham; Laura Kovanda; Katyna Borroto-Esoda; Steve Wring; David Angulo; Mahmoud Ghannoum
Journal:  Antimicrob Agents Chemother       Date:  2017-04-24       Impact factor: 5.191
  7 in total
  30 in total

1.  Penetration of Ibrexafungerp (Formerly SCY-078) at the Site of Infection in an Intra-abdominal Candidiasis Mouse Model.

Authors:  Annie Lee; Brendan Prideaux; Matthew Zimmerman; Claire Carter; Stephen Barat; David Angulo; Véronique Dartois; David S Perlin; Yanan Zhao
Journal:  Antimicrob Agents Chemother       Date:  2020-02-21       Impact factor: 5.191

Review 2.  Candida auris: a Review of the Literature.

Authors:  Anna Jeffery-Smith; Surabhi K Taori; Silke Schelenz; Katie Jeffery; Elizabeth M Johnson; Andrew Borman; Rohini Manuel; Colin S Brown
Journal:  Clin Microbiol Rev       Date:  2017-11-15       Impact factor: 26.132

3.  In Vitro Activity of Ibrexafungerp (SCY-078) against Candida auris Isolates as Determined by EUCAST Methodology and Comparison with Activity against C. albicans and C. glabrata and with the Activities of Six Comparator Agents.

Authors:  Maiken Cavling Arendrup; Karin Meinike Jørgensen; Rasmus Krøger Hare; Anuradha Chowdhary
Journal:  Antimicrob Agents Chemother       Date:  2020-02-21       Impact factor: 5.191

4.  In Vitro Interactions of Echinocandins with Triazoles against Multidrug-Resistant Candida auris.

Authors:  Hamed Fakhim; Anuradha Chowdhary; Anupam Prakash; Afsane Vaezi; Eric Dannaoui; Jacques F Meis; Hamid Badali
Journal:  Antimicrob Agents Chemother       Date:  2017-10-24       Impact factor: 5.191

5.  In Vitro Activity of Ibrexafungerp, a Novel Glucan Synthase Inhibitor against Candida glabrata Isolates with FKS Mutations.

Authors:  Natalie S Nunnally; Kizee A Etienne; David Angulo; Shawn R Lockhart; Elizabeth L Berkow
Journal:  Antimicrob Agents Chemother       Date:  2019-10-22       Impact factor: 5.191

6.  Enfumafungin synthase represents a novel lineage of fungal triterpene cyclases.

Authors:  Eric Kuhnert; Yan Li; Nan Lan; Qun Yue; Li Chen; Russell J Cox; Zhiqiang An; Kenichi Yokoyama; Gerald F Bills
Journal:  Environ Microbiol       Date:  2018-09-13       Impact factor: 5.491

Review 7.  Targeting the fungal cell wall: current therapies and implications for development of alternative antifungal agents.

Authors:  Sahar Hasim; Jeffrey J Coleman
Journal:  Future Med Chem       Date:  2019-04-17       Impact factor: 3.808

Review 8.  Emerging and future strategies in the management of recalcitrant Candida auris.

Authors:  Nihal Bandara; Lakshman Samaranayake
Journal:  Med Mycol       Date:  2022-03-17       Impact factor: 4.076

9.  Candida auris Pan-Drug-Resistant to Four Classes of Antifungal Agents.

Authors:  Samantha E Jacobs; Jonathan L Jacobs; Emily K Dennis; Sarah Taimur; Meenakshi Rana; Dhruv Patel; Melissa Gitman; Gopi Patel; Sarah Schaefer; Kishore Iyer; Jang Moon; Victoria Adams; Polina Lerner; Thomas J Walsh; YanChun Zhu; Mohammed Rokebul Anower; Mayuri M Vaidya; Sudha Chaturvedi; Vishnu Chaturvedi
Journal:  Antimicrob Agents Chemother       Date:  2022-06-30       Impact factor: 5.938

Review 10.  Mechanistic Insight into Antimicrobial and Antioxidant Potential of Jasminum Species: A Herbal Approach for Disease Management.

Authors:  Acharya Balkrishna; Akansha Rohela; Abhishek Kumar; Ashwani Kumar; Vedpriya Arya; Pallavi Thakur; Patrik Oleksak; Ondrej Krejcar; Rachna Verma; Dinesh Kumar; Kamil Kuca
Journal:  Plants (Basel)       Date:  2021-05-28
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