| Literature DB >> 28482480 |
Ming Zhang1, Cheng Chi1, Ping Yuan1, Yutian Su1, Maoni Shao1, Ninglin Zhou2.
Abstract
In this work, phosphor and nitrogen co-doped carbon dots (N-P-doped CDs) were developed for bioimaging. The as-synthesized N-P-doped CDs emit a bright blue coloured fluorescence after exposure to a 365nm UV-lamp illumination. It is also demonstrated that the fluorescence of CDs is resistant to the interference of metal ions, saline solution, and high ionic strength environments. The bright fluorescence nature of the N-P-doped CDs has proven them to be excellent probes for cellular imaging. And this guess is further confirmed by using a laser scanning confocal microscope (LSCM). The viability study was carried out by MTT assay, suggesting the high biocompatibility of N-P-doped CDs. The results demonstrated that N-P-doped CDs may be considered as a safe material for bio-imaging and drug delivery in cancer cells.Entities:
Keywords: Biocompatibility; Bioimaging; Cancer therapy; Drug delivery
Mesh:
Substances:
Year: 2017 PMID: 28482480 DOI: 10.1016/j.msec.2017.03.144
Source DB: PubMed Journal: Mater Sci Eng C Mater Biol Appl ISSN: 0928-4931 Impact factor: 7.328