Literature DB >> 28480909

Inhibition of d-Ala incorporation into wall teichoic acid in Staphylococcus aureus by desleucyl-oritavancin.

J Chang1, L Coffman, S J Kim.   

Abstract

The mode of action for desleucyl-oritavancin was investigated by adding an antibiotic to Staphylococcus aureus during its growth in a defined medium containing l,d-[1-15N]Ala and l-[1-13C]Lys, or d-[1-15N]Ala. 13C{15N} and 15N{13C} rotational-echo double resonance NMR determined that desleucyl-oritavancin inhibited the incorporation of d-[1-15N]Ala into wall teichoic acid.

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Year:  2017        PMID： 28480909      PMCID： PMC5512289          DOI： 10.1039/c7cc02635h

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  26 in total

1.  The D-alanine residues of Staphylococcus aureus teichoic acids alter the susceptibility to vancomycin and the activity of autolytic enzymes.

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Journal:  Antimicrob Agents Chemother       Date:  2000-10       Impact factor: 5.191

2.  The Carboxyl Terminus of Eremomycin Facilitates Binding to the Non-d-Ala-d-Ala Segment of the Peptidoglycan Pentapeptide Stem.

Authors:  James Chang; Hongyu Zhou; Maria Preobrazhenskaya; Peng Tao; Sung Joon Kim
Journal:  Biochemistry       Date:  2016-06-07       Impact factor: 3.162

3.  Rotational-echo double resonance characterization of vancomycin binding sites in Staphylococcus aureus.

Authors:  Sung Joon Kim; Lynette Cegelski; Daniel R Studelska; Robert D O'Connor; Anil K Mehta; Jacob Schaefer
Journal:  Biochemistry       Date:  2002-06-04       Impact factor: 3.162

4.  Desleucyl-Oritavancin with a Damaged d-Ala-d-Ala Binding Site Inhibits the Transpeptidation Step of Cell-Wall Biosynthesis in Whole Cells of Staphylococcus aureus.

Authors:  Sung Joon Kim; Manmilan Singh; Shasad Sharif; Jacob Schaefer
Journal:  Biochemistry       Date:  2017-03-03       Impact factor: 3.162

5.  Structures of Staphylococcus aureus cell-wall complexes with vancomycin, eremomycin, and chloroeremomycin derivatives by 13C{19F} and 15N{19F} rotational-echo double resonance.

Authors:  Sung Joon Kim; Lynette Cegelski; Maria Preobrazhenskaya; Jacob Schaefer
Journal:  Biochemistry       Date:  2006-04-25       Impact factor: 3.162

6.  REDOR constraints on the peptidoglycan lattice architecture of Staphylococcus aureus and its FemA mutant.

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Journal:  Biochim Biophys Acta       Date:  2014-06-02

7.  19F NMR in the measurement of binding affinities of chloroeremomycin to model bacterial cell-wall surfaces that mimic VanA and VanB resistance.

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Journal:  Chem Biol       Date:  1998-06

8.  Hydrophobic side-chain length determines activity and conformational heterogeneity of a vancomycin derivative bound to the cell wall of Staphylococcus aureus.

Authors:  Sung Joon Kim; Jacob Schaefer
Journal:  Biochemistry       Date:  2008-08-30       Impact factor: 3.162

9.  Pharmacodynamics of a simulated single 1,200-milligram dose of oritavancin in an in vitro pharmacokinetic/pharmacodynamic model of methicillin-resistant staphylococcus aureus infection.

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Journal:  Antimicrob Agents Chemother       Date:  2012-10-22       Impact factor: 5.191

10.  Cross-link formation and peptidoglycan lattice assembly in the FemA mutant of Staphylococcus aureus.

Authors:  Sung Joon Kim; Manmilan Singh; Shasad Sharif; Jacob Schaefer
Journal:  Biochemistry       Date:  2014-02-26       Impact factor: 3.162
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  3 in total

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Journal:  Sci Rep       Date:  2022-04-30       Impact factor: 4.996

2.  Peptidoglycan compositional analysis of Mycobacterium smegmatis using high-resolution LC-MS.

Authors:  Binayak Rimal; Sibusiso Senzani; Christopher Ealand; Gyanu Lamichhane; Bavesh Kana; Sung Joon Kim
Journal:  Sci Rep       Date:  2022-06-30       Impact factor: 4.996

3.  Dsi-RNA knockdown of genes regulated by Foxo reduces glycogen and lipid accumulations in diapausing Culex pipiens.

Authors:  Olatunde P Olademehin; Chengyin Liu; Binayak Rimal; Nathaniel F Adegboyega; Fu Chen; Cheolho Sim; Sung Joon Kim
Journal:  Sci Rep       Date:  2020-10-14       Impact factor: 4.379
  3 in total

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