Literature DB >> 28480709

Iridium-Catalyzed Direct Regioselective C4-Amidation of Indoles under Mild Conditions.

Shuyou Chen1, Boya Feng1, Xuesong Zheng1, Jiangliang Yin1, Shiping Yang1, Jingsong You1.   

Abstract

An efficient Ir-catalyzed amidation of indoles with sulfonyl azides is disclosed, affording diverse C4-amidated indoles exclusively under mild conditions. In this protocol, a variety of indoles with commonly occurring functional groups such as formyl, acetyl, carboxyl, amide, and ester at the C3 position are well tolerated.

Entities:  

Year:  2017        PMID： 28480709     DOI： 10.1021/acs.orglett.7b00730

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  5 in total

Review 1.  The Molecular Diversity of 1H-Indole-3-Carbaldehyde Derivatives and Their Role in Multicomponent Reactions.

Authors:  Ghodsi Mohammadi Ziarani; Samira Hasani; Fatemeh Mohajer; Rajender S Varma; Fatemeh Rafiee
Journal:  Top Curr Chem (Cham)       Date:  2022-04-25

Review 2.  A comprehensive overview of directing groups applied in metal-catalysed C-H functionalisation chemistry.

Authors:  Carlo Sambiagio; David Schönbauer; Remi Blieck; Toan Dao-Huy; Gerit Pototschnig; Patricia Schaaf; Thomas Wiesinger; Muhammad Farooq Zia; Joanna Wencel-Delord; Tatiana Besset; Bert U W Maes; Michael Schnürch
Journal:  Chem Soc Rev       Date:  2018-08-28       Impact factor: 54.564

Review 3.  C4-H indole functionalisation: precedent and prospects.

Authors:  Jagadeesh Kalepu; Parthasarathy Gandeepan; Lutz Ackermann; Lukasz T Pilarski
Journal:  Chem Sci       Date:  2018-04-20       Impact factor: 9.825

4.  Iridium-catalyzed regioselective C-H sulfonamidation of 1,2,4-thiadiazoles with sulfonyl azides in water.

Authors:  Xian-Ting Cao; Su-Ning Wei; Hao-Tian Sun; Meng Li; Zuo-Ling Zheng; Guannan Wang
Journal:  RSC Adv       Date:  2021-06-22       Impact factor: 4.036

Review 5.  Direct sulfonamidation of (hetero)aromatic C-H bonds with sulfonyl azides: a novel and efficient route to N-(hetero)aryl sulfonamides.

Authors:  Zhi Liu; Abdolghaffar Ebadi; Mohsen Toughani; Nihat Mert; Esmail Vessally
Journal:  RSC Adv       Date:  2020-10-08       Impact factor: 4.036
  5 in total

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