Literature DB >> 28480242

Outcomes Associated With Antimicrobial De-escalation of Treatment for Pneumonia Within the Veterans Healthcare Administration.

Jefferson G Bohan1, Richard Remington2,3, Makoto Jones4, Matthew Samore4, Karl Madaras-Kelly5,5.   

Abstract

De-escalation, an antimicrobial stewardship concept, involves narrowing broad-spectrum empiric antimicrobial therapy based on clinical data. Current health outcomes evidence is lacking to support de-escalation. Studying Veterans Healthcare Administration pneumonia patients, de-escalation was associated with improved length of stay without affecting 30-day readmission or 30-day Clostridium difficile infection rates.

Entities:  

Keywords:  antimicrobial stewardship; de-escalation; outcomes; pneumonia.

Year:  2016        PMID： 28480242      PMCID： PMC5414017          DOI： 10.1093/ofid/ofw244

Source DB:  PubMed          Journal:  Open Forum Infect Dis        ISSN： 2328-8957            Impact factor:   3.835


  12 in total

Review 1.  A Systematic Review of the Definitions, Determinants, and Clinical Outcomes of Antimicrobial De-escalation in the Intensive Care Unit.

Authors:  Alexis Tabah; Menino Osbert Cotta; Jose Garnacho-Montero; Jeroen Schouten; Jason A Roberts; Jeffrey Lipman; Mark Tacey; Jean-François Timsit; Marc Leone; Jean Ralph Zahar; Jan J De Waele
Journal:  Clin Infect Dis       Date:  2015-12-23       Impact factor: 9.079

2.  Unnecessary antimicrobial use in the context of Clostridium difficile infection: a call to arms for the Veterans Affairs Antimicrobial Stewardship Task Force.

Authors:  Christopher J Graber; Karl Madaras-Kelly; Makoto M Jones; Melinda M Neuhauser; Matthew Bidwell Goetz
Journal:  Infect Control Hosp Epidemiol       Date:  2013-06       Impact factor: 3.254

3.  Implementing an Antibiotic Stewardship Program: Guidelines by the Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America.

Authors:  Tamar F Barlam; Sara E Cosgrove; Lilian M Abbo; Conan MacDougall; Audrey N Schuetz; Edward J Septimus; Arjun Srinivasan; Timothy H Dellit; Yngve T Falck-Ytter; Neil O Fishman; Cindy W Hamilton; Timothy C Jenkins; Pamela A Lipsett; Preeti N Malani; Larissa S May; Gregory J Moran; Melinda M Neuhauser; Jason G Newland; Christopher A Ohl; Matthew H Samore; Susan K Seo; Kavita K Trivedi
Journal:  Clin Infect Dis       Date:  2016-04-13       Impact factor: 9.079

4.  Audit and Feedback Processes Among Antimicrobial Stewardship Programs: A Survey of the Society for Healthcare Epidemiology of America Research Network.

Authors:  D J Livorsi; B Heintz; J T Jacob; S L Krein; D J Morgan; E N Perencevich
Journal:  Infect Control Hosp Epidemiol       Date:  2016-03-10       Impact factor: 3.254

5.  Characteristics of Antimicrobial Stewardship Programs at Veterans Affairs Hospitals: Results of a Nationwide Survey.

Authors:  Ann F Chou; Christopher J Graber; Makoto Jones; Yue Zhang; Matthew Bidwell Goetz; Karl Madaras-Kelly; Matthew Samore; Allison Kelly; Peter A Glassman
Journal:  Infect Control Hosp Epidemiol       Date:  2016-02-24       Impact factor: 3.254

6.  Development of an antibiotic spectrum score based on veterans affairs culture and susceptibility data for the purpose of measuring antibiotic de-escalation: a modified Delphi approach.

Authors:  Karl Madaras-Kelly; Makoto Jones; Richard Remington; Nicole Hill; Benedikt Huttner; Matthew Samore
Journal:  Infect Control Hosp Epidemiol       Date:  2014-07-25       Impact factor: 3.254

7.  Safety and clinical outcomes of carbapenem de-escalation as part of an antimicrobial stewardship programme in an ESBL-endemic setting.

Authors:  Kaung Yuan Lew; Tat Ming Ng; Michelle Tan; Sock Hoon Tan; Ee Ling Lew; Li Min Ling; Brenda Ang; David Lye; Christine B Teng
Journal:  J Antimicrob Chemother       Date:  2014-12-03       Impact factor: 5.790

8.  Antimicrobial de-escalation of treatment for healthcare-associated pneumonia within the Veterans Healthcare Administration.

Authors:  Karl Madaras-Kelly; Makoto Jones; Richard Remington; Christina M Caplinger; Benedikt Huttner; Barbara Jones; Matthew Samore
Journal:  J Antimicrob Chemother       Date:  2015-11-03       Impact factor: 5.790

9.  Description and validation of a spectrum score method to measure antimicrobial de-escalation in healthcare associated pneumonia from electronic medical records data.

Authors:  Karl Madaras-Kelly; Makoto Jones; Richard Remington; Christina Caplinger; Benedikt Huttner; Matthew Samore
Journal:  BMC Infect Dis       Date:  2015-04-25       Impact factor: 3.090

10.  Impact of Antimicrobial Stewardship Program (ASP) on Outcomes in Patients with Acute Bacterial Skin and Skin Structure Infections (ABSSSIs) in an Acute-Tertiary Care Hospital.

Authors:  Li Wen Loo; Yi Xin Liew; Winnie Lee; Piotr Chlebicki; Andrea Lay-Hoon Kwa
Journal:  Infect Dis Ther       Date:  2015-09-11
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  6 in total

1.  Desirability of Outcome Ranking for the Management of Antimicrobial Therapy (DOOR MAT) Reveals Improvements in the Treatment of Bloodstream Infections Caused by Escherichia coli and Klebsiella pneumoniae in Patients from the Veterans Health Administration.

Authors:  Federico Perez; Roberto Viau Colindres; Brigid M Wilson; Elie Saade; Robin L P Jump; Ritu Banerjee; Robin Patel; Scott R Evans; Robert A Bonomo
Journal:  Clin Infect Dis       Date:  2021-10-05       Impact factor: 9.079

2.  Assessment of Antibiotic De-escalation by Spectrum Score in Patients With Nosocomial Pneumonia: A Single-Center, Retrospective Cohort Study.

Authors:  Dan Ilges; David J Ritchie; Tamara Krekel; Elizabeth A Neuner; Nicholas Hampton; Marin H Kollef; Scott Micek
Journal:  Open Forum Infect Dis       Date:  2021-11-17       Impact factor: 3.835

3.  Appropriateness of Antibiotics Use and Associated Factors in Hospitalized Patients at University of Gondar Specialized Hospital, Amhara, Ethiopia: Prospective Follow-up Study.

Authors:  Demssie A Anteneh; Zemene D Kifle; Gizeaddis B Mersha; Tewodros T Ayele
Journal:  Inquiry       Date:  2021 Jan-Dec       Impact factor: 1.730

4.  Impact of empirical oseltamivir discontinuation in hospitalized patients with community-acquired pneumonia after confirmed negative for influenza.

Authors:  Ashjan F Alghanem; Fahad A Aldhahri; Abdullah U Althemery
Journal:  Saudi Med J       Date:  2021-10       Impact factor: 1.422

5.  De-escalation of Empiric Antibiotics Following Negative Cultures in Hospitalized Patients With Pneumonia: Rates and Outcomes.

Authors:  Abhishek Deshpande; Sandra S Richter; Sarah Haessler; Peter K Lindenauer; Pei-Chun Yu; Marya D Zilberberg; Peter B Imrey; Thomas Higgins; Michael B Rothberg
Journal:  Clin Infect Dis       Date:  2021-04-26       Impact factor: 9.079

6.  Short and Concise Peer-to-Peer Teaching-Example of a Successful Antibiotic Stewardship Intervention to Increase Iv to Po Conversion.

Authors:  Johannes Wild; Bettina Siegrist; Lukas Hobohm; Thomas Münzel; Thomas Schwanz; Ingo Sagoschen
Journal:  Antibiotics (Basel)       Date:  2022-03-17
  6 in total

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