Literature DB >> 2847943

Human heart cytochrome c oxidase subunit VIII. Purification and determination of the complete amino acid sequence.

A B Van Kuilenburg1, A O Muijsers, H Demol, H L Dekker, J J Van Beeumen.   

Abstract

Subunit VIII was purified from a preparation of the human heart cytochrome c oxidase and its complete amino acid sequence was determined. The sequence proved to be much more related to that of the bovine liver oxidase subunit VIII than to that found in bovine heart. Our finding of a 'liver-type' subunit VIII in the human heart enzyme suggests that either there are no isoforms of human subunit VIII or the human oxidase does not show the type of tissue specificity that has been reported for the oxidase in other mammals.

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Year:  1988        PMID： 2847943     DOI： 10.1016/0014-5793(88)80353-3

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  10 in total

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  10 in total

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