| Literature DB >> 28478895 |
Neerja Yadav1, Munishwar Nath Gupta2, Sunil K Khare3.
Abstract
In the present study, a halophilic Bacillus subtilis subsp. spizizenii (NCBI GenBank accession number KX109607) was isolated from the Sambhar Salt Lake, Rajasthan India. This organism exhibited significance antibacterial and antifungal activity against Proteus vulgaris, Bacillus subtilis, Aspergillus niger, Rhizopus oligosporus and Penicillium chrysogenum respectively. The bioactive constituent responsible for it was extracted by three phase partitioning and purified by column chromatography. The purified compound was further characterized by FTIR-ATR, NMR and Mass spectrometry. The mass spectra show a molecular ion of m/z 301.14. The compound has very high antimicrobial activity showing 35mm zone of inhibition against Bacillus subtilis.Entities:
Keywords: Antimicrobial activity; Bacillus sp.; Bioactive peptide; Halophilies; Three phase partitioning
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Year: 2017 PMID： 28478895 DOI： 10.1016/j.biortech.2017.04.090
Source DB: PubMed Journal: Bioresour Technol ISSN： 0960-8524 Impact factor: 9.642