| Literature DB >> 28475866 |
Abstract
Chen et al. (2017) demonstrate whole-genome amplification of single-cell genomic DNA using linear nucleic acid amplification. This provides reliable single-nucleotide variation (SNV) detection across the single-cell genome, facilitating an understanding of cell-to-cell similarities and distinctions.Entities:
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Year: 2017 PMID： 28475866 DOI： 10.1016/j.molcel.2017.04.015
Source DB: PubMed Journal: Mol Cell ISSN： 1097-2765 Impact factor: 17.970