| Literature DB >> 28474489 |
Yong-Jian Chen1, Sen-Lin Cai1, Chuan-Chuan Wang1, Jin-Duo Cheng1, Søren Kramer2, Xing-Wen Sun1.
Abstract
An asymmetric route to (-)-α-lycorane and (-)-zephyranthine, and a formal total synthesis of (+)-clivonine were achieved. A pivotal intermediate, which serves as a potent precursor for the divergent syntheses of these natural products, was accessed by a diastereoselective Pd-catalyzed cinnamylation of an N-tert-butanesulfinyl imine.Entities:
Keywords: alkaloids; asymmetric synthesis; total synthesis; zephyranthine; α-lycorane
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Year: 2017 PMID： 28474489 DOI： 10.1002/asia.201700555
Source DB: PubMed Journal: Chem Asian J ISSN： 1861-471X