Literature DB >> 28474182

Homogenous scaffold-based cranial/skull implant modelling and structural analysis-unit cell algorithm-meshless approach.

V Phanindra Bogu1, Y Ravi Kumar2, Asit Kumar Khanra3.   

Abstract

This computational study explores a unique modelling approach of the cranial implant, homogenous scaffold algorithm and meshless method, respectively. This meshless method is employed to review the implant underneath intracranial pressure (ICP) conditions with a standard ICP range of 7 mm of Hg to 15 mm of Hg. The algorithm is used to introduce uniform porosity within the implant enabling the implant behaviour with respect to ICP conditions. However, increase in the porosity leads to variation in deformation and equivalent stress, respectively. The meshless approach provides a valuable insight in order to know the effect of total deformation and equivalent stress (von Mises stress) and replaces the standard meshing strategies. The patient CT data (computed tomography) is processed in MIMICS software to get the mesh model. An entirely unique modelling approach is developed to model the cranial implant with the assistance of the Rhinoceros software. This modelling methodology is the easiest one and addressing both the symmetrical and asymmetrical defects. The implant is embedded in a unit cell-based porous structure with the help of an algorithm, and this algorithm is simple to manage the consistency in porosity and pore size of the scaffold. Totally six types of implants are modelled with variation in porosity and replicate the original cranial bone. Among six implants, Type 2 (porosity 82.62%) and Type 5 (porosity 45.73%) implants are analysed with the meshless approach under ICP. The total deformation and equivalent stress (von Mises stress) of porous implants are compared with the solid implant under same ICP conditions. Consequently, distinctive materials are used for structural analysis such as titanium alloy (Ti6Al4V) and polyether-ether-ketone (PEEK), respectively. The deformation and equivalent stress (von Mises stress) results are obtained through the structural analysis. It was observed from the results that the titanium-based solid implant is the best implant in all aspects, while considering weight and osseointegration PEEK-based Type 5 implant is the best one. A novel free-form closed curve network (FCN) technique is successfully developed to model a cranial implant for symmetrical and asymmetrical defects. The porous implant is adequately modelled through the unit cell algorithm and analysed through meshless approach. The implementation of 3D printed component will allow physicians to gain knowledge and successfully plan the preoperative surgery.

Entities:  

Keywords:  Intracranial pressure; Meshless method; Scaffold algorithm; Symmetrical and asymmetrical defects; Unit cell parameters

Mesh:

Substances:

Year:  2017        PMID: 28474182     DOI: 10.1007/s11517-017-1649-3

Source DB:  PubMed          Journal:  Med Biol Eng Comput        ISSN: 0140-0118            Impact factor:   2.602


  22 in total

1.  The effect of pore geometry on the in vitro biological behavior of human periosteum-derived cells seeded on selective laser-melted Ti6Al4V bone scaffolds.

Authors:  S Van Bael; Y C Chai; S Truscello; M Moesen; G Kerckhofs; H Van Oosterwyck; J-P Kruth; J Schrooten
Journal:  Acta Biomater       Date:  2012-04-07       Impact factor: 8.947

2.  Extracting clinically relevant data from finite element simulations.

Authors:  Marco Viceconti; Sigbjorn Olsen; Lutz-P Nolte; Kim Burton
Journal:  Clin Biomech (Bristol, Avon)       Date:  2005-06       Impact factor: 2.063

Review 3.  Monitoring the injured brain: ICP and CBF.

Authors:  L A Steiner; P J D Andrews
Journal:  Br J Anaesth       Date:  2006-05-12       Impact factor: 9.166

4.  Micro-CT-based screening of biomechanical and structural properties of bone tissue engineering scaffolds.

Authors:  Tim Van Cleynenbreugel; Jan Schrooten; Hans Van Oosterwyck; Jos Vander Sloten
Journal:  Med Biol Eng Comput       Date:  2006-06-27       Impact factor: 2.602

5.  Variation of bone layer thicknesses and trabecular volume fraction in the adult male human calvarium.

Authors:  Sourabh Boruah; Glenn R Paskoff; Barry S Shender; Damien L Subit; Robert S Salzar; Jeff R Crandall
Journal:  Bone       Date:  2015-04-25       Impact factor: 4.398

6.  Estimation of skull table thickness with clinical CT and validation with microCT.

Authors:  Elizabeth M Lillie; Jillian E Urban; Ashley A Weaver; Alexander K Powers; Joel D Stitzel
Journal:  J Anat       Date:  2014-12-01       Impact factor: 2.610

7.  Modelling and structural analysis of skull/cranial implant: beyond mid-line deformities.

Authors:  V Phanindra Bogu; Y Ravi Kumar; Asit Kumar Khanara
Journal:  Acta Bioeng Biomech       Date:  2017       Impact factor: 1.073

8.  Computed-tomography modeled polyether ether ketone (PEEK) implants in revision cranioplasty.

Authors:  Eamon B O'Reilly; Sam Barnett; Christopher Madden; Babu Welch; Bruce Mickey; Shai Rozen
Journal:  J Plast Reconstr Aesthet Surg       Date:  2014-11-21       Impact factor: 2.740

9.  Cranial reconstruction: 3D biomodel and custom-built implant created using additive manufacturing.

Authors:  André Luiz Jardini; Maria Aparecida Larosa; Rubens Maciel Filho; Cecília Amélia de Carvalho Zavaglia; Luis Fernando Bernardes; Carlos Salles Lambert; Davi Reis Calderoni; Paulo Kharmandayan
Journal:  J Craniomaxillofac Surg       Date:  2014-08-06       Impact factor: 2.078

10.  Thickness of the human cranial diploe in relation to age, sex and general body build.

Authors:  Niels Lynnerup; Jacob G Astrup; Birgitte Sejrsen
Journal:  Head Face Med       Date:  2005-12-20       Impact factor: 2.151

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