Literature DB >> 28474016

Intratumoral H2O2-triggered release of CO from a metal carbonyl-based nanomedicine for efficient CO therapy.

Zhaokui Jin1, Yanyuan Wen, Liwei Xiong, Tian Yang, Penghe Zhao, Liwei Tan, Tianfu Wang, Zhiyong Qian, Bao-Lian Su, Qianjun He.   

Abstract

A new H2O2-responsive nanomedicine for CO therapy is constructed by effectively encapsulating the hydrophobic manganese carbonyl prodrug into an advanced hollow mesoporous silica nanoparticle carrier to realize the intratumoral H2O2-triggered release of CO and selective killing of tumour cells rather than normal cells, exhibiting high in vitro and in vivo efficacies of CO therapy.

Entities:  

Year:  2017        PMID： 28474016     DOI： 10.1039/c7cc01576c

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  6 in total

1.  Development of Triggerable, Trackable, and Targetable Carbon Monoxide Releasing Molecules.

Authors:  Livia S Lazarus; Abby D Benninghoff; Lisa M Berreau
Journal:  Acc Chem Res       Date:  2020-09-15       Impact factor: 22.384

2.  Programmed ROS/CO-releasing nanomedicine for synergetic chemodynamic-gas therapy of cancer.

Authors:  Bin Zhao; Penghe Zhao; Zhaokui Jin; Mingjian Fan; Jin Meng; Qianjun He
Journal:  J Nanobiotechnology       Date:  2019-06-13       Impact factor: 10.435

3.  Generic synthesis of small-sized hollow mesoporous organosilica nanoparticles for oxygen-independent X-ray-activated synergistic therapy.

Authors:  Wenpei Fan; Nan Lu; Zheyu Shen; Wei Tang; Bo Shen; Zhaowen Cui; Lingling Shan; Zhen Yang; Zhantong Wang; Orit Jacobson; Zijian Zhou; Yijing Liu; Ping Hu; Weijing Yang; Jibin Song; Yang Zhang; Liwen Zhang; Niveen M Khashab; Maria A Aronova; Guangming Lu; Xiaoyuan Chen
Journal:  Nat Commun       Date:  2019-03-18       Impact factor: 14.919

4.  A multistage assembly/disassembly strategy for tumor-targeted CO delivery.

Authors:  Jin Meng; Zhaokui Jin; Penghe Zhao; Bin Zhao; Mingjian Fan; Qianjun He
Journal:  Sci Adv       Date:  2020-05-15       Impact factor: 14.136

Review 5.  Carbon monoxide and a change of heart.

Authors:  Louis M Chu; Shazhad Shaefi; James D Byrne; Rodrigo W Alves de Souza; Leo E Otterbein
Journal:  Redox Biol       Date:  2021-11-08       Impact factor: 11.799

Review 6.  Emerging nanobiotechnology for precise theranostics of hepatocellular carcinoma.

Authors:  Mengjiao Xu; Liu Yang; Yanjie Lin; Yao Lu; Xiaoyue Bi; Tingting Jiang; Wen Deng; Lu Zhang; Wei Yi; Yao Xie; Minghui Li
Journal:  J Nanobiotechnology       Date:  2022-09-29       Impact factor: 9.429
  6 in total

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